Abstract
The material of the study was 16 weaned piglets that died at the age of 27–45 days, and samples of full-fledged granular mixed feed SK-3 – prestarter for piglets aged 10–42 days, fed in groups of the studied animals. Pathoanatomic examination and histological examination of lung, liver and kidney samples were performed. Conducted a study of the feed for the presence of fumonisins by high-performance liquid chromatography-mass spectrometry (HPLC-MS/MS) by using Agilent 1290/AB SCIEX Triple Quad 5500 GOST 34140-2017. As a result of the study, it was established that about 4 mcg of fumonisins per 1 kg of weight were received into the body of the studied piglets per day with mixed feed at an acceptable rate of 2 mcg/kg, i.e. the daily dose of fumonisins exceeded the permissible dose by 2 times. At the autopsy, pulmonary edema, asphyxiated heart, protein liver dystrophy with foci of necrosis, catarrhal enteritis, cloudy swelling of the kidneys were found in piglets. Histological examination in the liver of piglets revealed granular dystrophy and necrosis of hepatocytes, and in some animals also leukocyte infiltration of parenchyma, in the kidneys, in the epithelial cells of the renal tubules – granular dystrophy and necrosis, in the lungs – accumulation of edematous fluid in the alveoli and bronchi.
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