우산나물 뿌리와 지상부 열수 추출물의 항산화 활성

Abstract

This study was performed in order to investigate the antioxidant properties of hot water extract from the root and aerial part of the Syneilesis palmata in respect to its potential use as food, cosmetics material, or medicinal resource. The results showed that the S. palmata root hot water extract (RHW) possessed a higher content of total flavonoid compounds (4.58 mg/g) and total polyphenol compounds (59.11 mg/g). The SOD-like activities of the RHW and APHW were 23.74% and 21.61%, respectively, at a concentration 2,000 ug/mL. In the nitrite scavenging ability of a 2,000 μg/mL concentration, the RHW showed 63.06% (pH 1.2) and 47.16% (pH 3.0). The IC50 values of the nitrite scavenging abilities were 99.93 μg/mL (ascorbic acid), 1,150.85 μg/mL (RHW), and 1,610.25 μg/mL (APHW). The IC50 values of DPPH free radical scavenging abilities were 99.87 μg/mL (RHW) and 118.29 μg/mL (APHW). The inhibition values (IC50) of xanthine oxidase were 139.62 μg/mL (RHW) and 111.11 μg/mL (APHW). In all of the experiments, the S. palmata root hot water extracts have higher activities than the aerial hot water extract, except for the xanthine oxidase inhibitory activity. These results suggest that the S. palmata is a potentially useful antioxidant source for the development of functional nutraceuticals, cosmetics and medicine.