비만 표현형에 따른 비만 치료의 기능의학적 접근

Abstract

According to recent studies, it has become evident that there is diversity in how the individuals, from a metabolic point of view, are affected by obesity. Difference in pathophysiology for each phenotype of obesity, may confer need for tailored approaches for the phenotype to maximize treatment effects. This narrative review, based on functional medicine, try to elucidate distinct feature of each phenotype of obesity and suggests a new approach which integrates body metabolism, energy balance into obesity management, in order not just to reduce body weight but also dissolve body fat which is a center of obesity pathophysiology. This approach leads to personalized treatment that work best for each obesity phenotype in reducing the risk of non-communicable diseases in clinical practice.