Анализ химического состава продуктов разложения российского вещества VX в условиях каталитического метанолиза

Abstract

Analytical platform for the testing new decontaminating formulations, involving identification of toxic destruction products and determination of the depth of decontamination under conditions mimicking real decontamination scenarios, was developed. The possibility of application of catalytic methanolysis for destruction of a highly toxic compound О -isobutyl S -[2-( N,N -diethylamino)ethyl] methylphosphonothioate referred to Russian VX (hereinafter, RVX) in homogeneous and heterogeneous reaction media are studied. Conditions for extraction of residual RVX from the reaction mixture, as well as GC−MS analysis of RVX were found and optimized. Destruction products of RVX, formed by its La-catalyzed methanolysis were identified. Efficiency of the catalytic formulation for decontamination of RVX-contaminated plastic surfaces was studied. The obtained results provide evidence for a high efficiency of the catalytic methanolysis for chemical neutralization of RVX and allow this process to be recommended for decontamination of engineering equipment. Key words: toxic organophosphorus compounds, VX-group compounds, catalytic methanolysis, gas chromatography−mass spectrometry, decontamination (Russian) L.K. Gustyleva, E.I. Savel’eva, N.S. Khlebnikova, A.S. Radilov Research Institute of Hygiene, Occupational Pathology and Human Ecology Federal State Unitary Enterprise Federal Medical Biological Agency, p/o Kus’molovsky, Leningrad Region, Russian Federation