Abstract

Study Objective: To evaluate the indicators of rotational thromboelastometry tests (ROTEM) in pregnant women in the third trimester and determine their reference values. Study Design: Prospective study. Materials and methods. Examination of 49 patients in the third trimester of pregnancy was conducted. The comparison group included 25 women of fertile age without concomitant somatic pathology. The study evaluated the results of INTEM, EXTEM, FIBTEM tests of rotational thromboelastometry on the ROTEM Delta analyzer. Study Results. Significant differences in all parameters of thromboelastometry in the INTEM, EXTEM and FIBTEM tests were obtained between the control group and women in the third trimester of pregnancy (p < 0.05), demonstrating physiological, chronometric and structural hypercoagulation, which must be taken into account when conducting therapy in obstetric practice. Conclusion. The data obtained can be used by practitioners of perinatal centers and maternity hospitals in everyday clinical practice, in the diagnosis and intensive care of coagulopathic obstetric bleeding. Keywords: rotational thromboelastometry, pregnancy, hemostasis, coagulopathy, hypercoagulation.

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