Таксономічна характеристика РНК-геномних вірусів хребетних тварин і людини

Abstract

The article presents a modern taxonomy and nomenclature of viruses of vertebrates animals and human based on information ICTV release 2016 (ratification 2017). Described the basic criteria for the classification of viruses: characteristics of the viral genome, the mechanism of replication and virions structure. Viruses of vertebrates (1269 species) consist of 5 orders, 38 families, including 12 – DNA-genomic and 26 – RNA-genomic, 12 subfamilies and 233 genera. RNA-genomic viruses of vertebrates (679 species) classified of 4 orders, 26 families, 6 subfamilies and 119 genera. The order Mononegavirales has united family Paramyxoviridae, Pneumoviridae, Rhabdoviridae, Filoviridae, Bornaviridae, Nyamiviridae and Sunviridae, order Nidovirales – family Coronaviridae and Arteriviridae, order Bunyavirales –family Hantaviridae, Nairoviridae, Peribunyaviridae and Phenuiviridae, order Picornavirales – family Picornaviridae. Family Rhabdoviridae, Nodaviridae, Peribunyaviridae, Phenuiviridae, Reoviridae and Birnaviridae, except viruses of vertebrates, contain viruses of insects, and family Rhabdoviridae, Phenuiviridae and Reoviridae – viruses of plants. There is а one of «floating» genus Deltavirus, which is not included of families. The family Reoviridae includes the Eriocheir sinensis reovirus, and the family Birnaviridae – Tellina virus. Described the taxa of viruses: family, subfamily, genera, species. Named typical species genera of viruses. Characterized the basic taxonomic features of RNA-genomic vertebrates viruses of animals and human: the shape, size and structure of virions – the presence of outer membrane lipoprotein, capsid symmetry type (spiral, icosahedral), the structure of the viral RNA (the number of threads, conformation, fragmentation, polarity). The attention to virus reproduction features. Replication of most RNA-genomic viruses occurs in cells of the cytoplasm, except for the representatives of the families Bornaviridae, Nyamiviridae, Orthomyxoviridae, Retroviridae and «floating» genus Deltavirus, which are replicated in the nucleus. Output of the progeny virions in simply organized viruses is due to cell destruction, and in most of the complexly organized viruses – plasma membrane buds, as well as through the membranes of the Golgi complex or the endoplasmic net in combination with exocytosis (Peribunyaviridae, Hantaviridae, Nairoviridae, Phenuiviridae, Flaviviridae, Coronaviridae, Arteriviridae).