Abstract
본 연구는 일회성 점증부하에 의한 혈액 세포내 항산화 효소 발현을 비만인과 정상인을 대상으로 운동의 효과에 대한 생화학 적응을 밝히는데 그 목적을 두고 시도되었다. 본 연구에 참가한 피험자는 본 연구의 목적을 충분히 이해하고 자발적인 참여를 원하는 비만인 8명과 정상인 8명의 총 16명이었다. 정상인 집단 8명은 특별한 대사성 질환이나 근골격계 질환이 없었으며, 비만여부의 판정기준은 체지방율 25% 이상으로 하였다. 피험자들의 혈액은 안정시, 운동직후, 그리고 회복기에 각각 자료처리 분석을 위해 집단 간 시기별 측정치의 차이분석을 위해 공변량분석을 실시하였다. 본 연구결과, 운동직후 정상인이 SOD 활성이 비만인 보다 통계적으로 높게 나타났다 (p<0.05). 일회성 운동이 비만인의 항산화 효소 활성보다 정상인의 항산화 효소 활성을 높게 한다는 결과는 운동직후 정상인의 ROS 생성이 활발해짐과 동시에 항산화 체제가 활성화되어 활성산소의 중화제 역할을 수행하는 것으로 사료된다. The purpose of this study was to identify the effects of acute exercise on antioxidative enzymes in noramal and obese men. The written informed consent was obtained from 16 participants of eight normally healthy persons and eight obesity ones. The baseline level of obesity was determined at 25 % of the body fat. Any subjects had no experiences in participating in exercise and did not take vitamin or mineral supplement. Blood was sampled at five minutes before exercise, at exhaustion, and after 30 minutes of recovery. All statistical analyses and description methods were computed by SPSS window 14.0. Analysis of Covariance(ANCOVA) was performed to know the differences in values between pre- and post- exercise in each group. We found that after exhaustion, the normal group showed higher erythrocyte superoxide dismutase (SOD) activity compared to the obesity group. At exhaustion, the normal group had lower HSP activity compared to the obesity group. Based on the results, an acute exercise of normally healthy people induced an up-regulation of superoxide dismutase (SOD) activity. This plays an important role in the protection of extra-cellular fluid components against peroxide-mediated damage.
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