Effects of acute exercise and aerobic exercise training on oxidative stress in young men and women

Abstract

This research investigated the effect of acute exhaustive exercise and exercise training on thiobarbituric acid-reactive substances (TBARS), protein carbonyl (PC), total glutathione (GSH) levels and total superoxide dismutase (SOD) activities. Thirty-two healthy young men and women, 19 to 27 years old, who volunteered to participant in this study, underwent two months of endurance training. The training program consisted of cycling exercises for 60 min, four times a week. Before and after the training course, they performed acute exhaustive exercise, and blood samples were collected immediately before, immediately after and 30 min after this exercise. The training significantly increased maximal oxygen uptake in the training groups. Also, body weight did not change in any of the groups. TBARS, PC and GSH levels were significantly affected by acute exercise in both women and men. However, acute exercise increased the activities of total SOD in women. Also, in men, the changes in SOD activity during acute exercise were significantly different between the control and training groups. There was no significant interaction effect among time, acute exercise and group for the TBARS, PC, GSH levels and SOD activities in either the women or men. These results indicate that the lipid and protein damage in response to acute exercise was not altered by aerobic exercise-training.