Abstract
Microorganisms' resistance to antibacterial drugs is now a major threat to human health and public health. The aim of the work was to conduct a comparative study of the species composition and resistance to antimicrobial treatments of microorganisms isolated from patients during the pandemic of the new coronavirus infection in 2020 with that from patients in 2019. The work examined bacterial strains isolated from patients with bacterial complications from COVID-19 in the intensive care unit of the Infectious Diseases Center in 2020 and from patients of the same departments treated before the pandemic of new coronavirus infection in 2019. It has been found that the species composition and resistance of microorganisms, received from patients during the pandemic in 2020, differs from those received from patients of the same departments of the same hospital in 2019. The number of polyresistent and panresistent microorganisms has increased significantly, bacterial microflora redistributed to responsible bronchopulge complications, in biomaterial, including bronchoalveolar lavage, increased the number of yeast fungi. Monitoring of microbiological strains will allow us to analyze the structure of pathogens in a particular unit, levels of their resistance to antimicrobials, as well as to identify the distribution mechanisms of microflora. The findings will facilitate the prescribing of rational empirical antimicrobial therapy and the planning of proactive measures to prevent the spread of hospital infection.
Published Version
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