Abstract

The article presents data on the level of expression of immune defense genes in normotrophic and hypotrophic piglets. 20 sows of 3–4 farrows and the offspring obtained from them were selected for the experiment. The piglets underwent clinical examination and weighing. Not reaching 800 g animals were counted as piglets-hypotrophic, animals over 800 g – respectively normotrophic. In the blood of normotrophic and hypotrophic piglets, the gene expression levels of IL-1β, TGF-β and TNF-α have minor changes: an increase in hypotrophic piglets by 1.2 and 1.1 times. However, the level of expression of the IFN-α gene in hypotrophic piglets was 4.2 times higher than in normotrophic piglets, which may be due to the immune response against the background of malnutrition, namely possible pyrogenicity.

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