Abstract
Annotation: suicide – can be considered as a reaction in a stressful situation. The decisive role in the development of the stress reaction belongs to the hypothalamichipophysealadrenal system. Materials and methods: the content of corticoliberin, adrenocorticotropic hormone and cortisol in the peripheral blood of persons who committed suicidal attempts. The comparison group (GC) consisted of persons who experienced stress, who had not previously committed. The presence of a statistical relationship between the study groups was tested using the nonparametric Kruskal-Wallis test. Pairwise comparison of distributions by the Mann-Whitney test with Bonferroni correction for the level of significance. When identifying the relationship by non-parametric criteria, an additional one-way analysis of variance was performed, which makes it possible to compare the average values of the indicators. Results: in males, an increase in the hypothalamic-hipophyseal-adrenal system hormones is noted. Statistically significant differences in hormone cortisol were found between GC and the group of people who used highly lethal methods of self-harm and are based on the differences in the group of men over 40 years old. In females, no statistically significant differences were found between the groups. Cunclusion: 1. Statistically significant differences between the groups were noted in the severity of motivation to commit suicide and the hormone Cortisol. 2. Statistically significant differences in the hormone Cortisol were due to the presence of differences between males over 40 years old. 3. In females, there were no statistically significant differences between hormonal indices.
Published Version
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