Abstract
The purpose of this article is studying biocompatibility of construction material of dental prostheses used in type 2 diabetes mellitus prosthodontic care. The article provides the analysis of findings concerning proteolytic activity of oral fluid in patients with type 2 diabetes when exposed to cobalt-chromium and nickel-chromium alloys of dental prostheses . According to the findings, usage of fixed whole piece prostheses intensifies proteolysis as the data of trypsin-like, elastic-like and entitripic activities of oral fluid attest.
 The results obtained during the study allow for a differentiated approach to the choice of constuction materials for prosthodontic treatment of patients with type 2 diabetes mellitus.
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