Abstract

Differential bone marrow cell count is a fundamental step in diagnostic hematology. The identification of metastatic carcinoma cells in sternal aspirates can be technically difficult with routine microscopy. Due to the morphological similarity of poorly differentiated carcinoma cells with young hematopoietic cells, the fact of metastasis can be easily missed or misinterpreted. It is even more difficult to detect micrometastases due to their uneven distribution over the smear, especially outside the imaging area, which leads to an erroneous diagnosis.

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