ЭФФЕКТИВНОСТЬНЕКОТОРЫХ ПИРЕТРОИДНЫХ ПРЕПАРАТОВ ПРИ КЛИНИЧЕСКОЙ ФОРМЕ ГИПОДЕРМАТОЗА КРУПНОГО РОГАТОГО СКОТА ВТЮМЕНСКОЙОБЛАСТИ

Abstract

There are two types of bovine warble flies in the Tyu-men Region: Hypoderma bovis and Hypoderma lineatum. The larvae of these insects cause significant harm to ani-mals, and farms bear significant economic damage due to decreased meat and dairy productivity of cattle and dam-age to leather raw materials. Ivermectin-based drugs are the most efficient means of controlling these pests. How-ever, recently, within the former Soviet Union and beyond, there were reports on the development of resistance in some insect species, including gadflies, to avermectin-typepreparations. In this regard, it is relevant to search for larvi-cides from other chemical groups that are efficient against the diseases caused by bovine warble flies. The research goal was to test the larvicidal activity of some preparations from the group of synthetic pyrethroids in comparison with the recommended means of controlling mature warble fly larvae by pour-on method. To exterminate mature larvae in fattening steers spontaneously infected with the parasites,Hypodectin-Nwas used; to compare the effectiveness, pyrethroid-based preparations were used: Ectomin -0.5% aqueous emulsion of Cypermethrin, Ectopor -2% solution of Cypermethrin, and Purofen -3% solution of Esfen-valerate, all ready to use. The solutions were applied to the skin of animal backs on both sides of the vertebral column using a syringe dispenser in a dose of 15 mL. The experi-ments have shown that the preparations of Cypermethrin and Fenvalerate prepared on the basis of organic solvents have high lipophilicity which ensures long-term preserva-tion of pyrethroids on the skin and their penetration into the capsules of the larvae of the hypodermal layer. Larvicidal efficiency of Ectopor and Purofen made 89.9 and 95.6%, respectively, while the activity of Hypodectin-Nmade 95.4%. Toxicological studies have shown that pyrethroid preparations do not cause irritation and destruction of the epidermis and hair of the skin, do not change the clinical status of steers and hematological indices of the treated animals. The obtained data allow advising Ectopor and Purofen for late chemotherapy of bovine hypodermatosis by pour-on methodin a dose of 15 mL per animal.