Abstract
The aim of this study was to evaluate the antioxidant activities and cytotoxicities of Actinidia polygama fruit extracts (AP) obtained using two extraction methods on cancer cells. AP yield was greater for an 80% ethanol extract than for a water extract (38.76% vs. 37.50%). Total polyphenolic and total flavonoid contents in AP obtained by ethanol extraction (AP-EE) were greater than those obtained by water extraction (AP-WE). Free radical scavenging activity and reducing power were greater for AP-EE than AP-WE. Mean antioxidant activities of AP-EE and AP-WE (1.0 ㎎/mL) as determined by the FRAP method were 28.57 and 27.50 μM, respectively. Furthermore, both AP-EE and AP-WE AP at 0.1 ㎎/mL inhibited the proliferation of MCF-7 and HeLa cancer cell lines for 48 hours. The study shows AP-EE and AP-WE have potential use as antioxidant and anticancer agents.
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