Abstract
The article presents the development of conditions for cell experiments using the Operetta CLS™ imaging system. The significance of high-content analysis parameters is substantiated. The optimal concentration and time parameters for the treatment of the cell culture of human colorectal carcinoma HCT116 by MDM2-p53 protein-protein interaction inhibitors were selected. The effect of the studied substances on cell growth was analyzed using Operetta CLS™.
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Schedule a callMore From: Bulletin of the Saint Petersburg State Institute of Technology (Technical University)
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