Abstract
Pregnancy is accompanied by physiological hemodynamic changes (an increase in circulating blood volume, stroke volume, cardiac output, heart rate), autonomic (an increase in plasma concentrations of catecholamines, an increase in the sensitivity of adrenergic receptors) and hormonal changes (an increase in the synthesis of estrogen, progesterone, prostaglandins, reninogen, angiotensin) ... All this can contribute to a change in the excitability, automatism and refractoriness of the myocardium, lead to the development and / or an increase in its electrophysiological inhomogeneity and, thus, provoke and / or aggravate the course of an already existing arrhythmia. This article will consider the relevance of the problem of the clinical and prognostic significance of extrasystolic arrhythmia in pregnant women without structural heart damage. The goal of increasing the efficiency of predicting the course of ventricular extrasystole without structural heart lesions in pregnant women at various periods of gestation in terms of thyroid and cardiovascular hormones will be proposed. The study of indicators of pregnancy hormones in pregnant women at different gestational periods with ventricular extrasystole without structural heart damage, the study of indicators of the sinus node, atrioventricular node and refractory periods of the cardiac conduction system in pregnant women is an urgent issue for research at the present time.
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