Поширеність вірусу папіломи людини серед хворих з інфекціями, що передаються статевим шляхом

Abstract

The affinity of sources of infection, dominance of sexual transmission, as well as the contingent of persons at risk of sexually transmitted infections (STIs) and human papilloma virus (HPV), determines the possibility of simultaneous infection with pathogens of these diseases. The aim of the study was to study the prevalence of highly oncogenic (HO) types of human papilloma virus among sick women with sexually transmitted infections and opportunistic flora (UTI). Materials and methods. The frequency of detection of highly oncogenic human papillomavirus types and their genotypes was assessed in 44 women (mean age 32.6 years) with chronic endocervicitis of mixed etiology using real-time polymerase chain reaction (PCR). Results. The initial prevalence (59.1%) of highly oncogenic human papillomavirus genotypes (16, 18, 31, 35, 45, 56, 58, 59, 66, 68, 82) was found among women of childbearing age with endocervicitis of Trichomonas etiology in combination with other (68.2%) sexually transmitted infections (chlamydia – 18.1%, ureaplasmosis – 25%) and opportunistic flora (86.4%), with a predominance of human papilloma virus type 16 (18.1%) and type 45 (15.9%). Conclusions. Diagnosing co-infection with sexually transmitted infections, opportunistic pathogens, and highly oncogenic types of human papillomavirus is an important factor in detecting cervical cancer.