Використання наночасток гідроксилапатиту стронцію для профілактики та лікування підвищеної стертості зубів (лабораторні дослідження)

Abstract

Summary. The paper describes a method for strontium hydroxyapatite nanoparticles for the prevention and treatment of high abrasion of teeth with minimum size of the primary particles with a high degree of aggregation and the penetration of nanoparticles into the crystal lattice of the tooth enamel, which is provided by increasing the density of the enamel layer the effectiveness of treatment and prevention of high abrasion of teeth.The aim of the study – development of several derivatives of strontium salts having different structure of nanoparticles for the purpose of their further integration into the enamel layer to increase the enamel strength.Materials and Methods. On the basis of the proposed method we designed research protocol samples of teeth with increased abrasion to assess the penetration and fixation of nanoparticles on the surface of the tooth enamel. The use of the proposed method in a dental practice would improve the effectiveness of treatment and prevention of high abrasion of teeth due to inclusion in the complex treatment in the form of applications, ointments and gels.Results and Discussion. We obtained nanoparticles synthesized from strontium nitrate in the form of prisms measuring from 30 nm to 34 nm in size obtained by precipitation from strontium chloride.Conclusions. As a result of experimental research, strontium hydroxylapatite nanostructures from anion derivatives (chloride, nitrate, acetate) were discovered. Microscopic investigation showed that they consisted of plates, needles and equiaxed particles with dimensions from 19.4 to 35 nm, which is confirmed by X-ray, trace studies and microscopic studies.