Abstract

Purpose. To identify the initial OCT parameters that allow determining the tactics of treating patients with chronic central serous chorioretinopathy complicated by pachychoroidal neovasculopathy. Material and methods. 73 patients (n = 73) with monolateral chronic form of central serous chorioretinopathy complicated by pachychoroidal neovasculopathy. All patients were given intravitreal angiogenesis inhibitors as initial therapy. Depending on the results of treatment, the patients were divided into groups: control – 39 (n = 39) patients with positive dynamics for the treatment used, the main group – 34 (n = 34) patients with the lack of the desired effect from intravitreal administration of angiogenesis inhibitors, who were treated of combined treatment with the connection of subthreshold micropulse laser exposure. Initial OCT parameters which were different for both groups were being found. Results. In the main group, exacerbation of central serous chorioretinopathy had a greater impact than subactive choroidal neovascularization 1, that determined the positive result of combined treatment. Characteristic for the main group of OCT predictors were the thickness of the choroid more than 470 µm, the area of choroidal neovascularization type 1 less than 0.27 mm², the height of detachment of the neurosensory retina more than 310 µm. The initial OCT parameters, typical for patients in the control group, were the subfoveolar thickness of the choroid less than 470 µm, the area of the choroidal neovascular membrane more than 0.27 mm², and the maximum height of neurosensory retinal detachment less than 310 µm. In patients of this group, the prevailing element of the current clinical condition was the activation of type 1 of pachychoroidal neovascular membrane, which determined the favorable functional results of anti-VEGF therapy. Conclusion. During the study, OCT parameters were identified that make it possible to timely determine the tactics of treating patients with a chronic form of central serous chorioretinopathy complicated by pachychoroidal neovasculopathy. Keywords: chronic central serous chorioretinopathy, pachychoroidal neovasculopathy, optical coherence tomography

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