Изменение лабораторных показателей липидного обмена у пациентов с ВИЧ-инфекцией при церебральном инсульте

Abstract

The article reflects the results of assessing the state of the blood lipid spectrum in HIV-positive patients with various types of stroke. Objective: to study laboratory parameters of lipid metabolism in patients with cerebral stroke against the background of HIV infection. Materials and methods. We examined 77 patients with ischemic and 32 patients with hemorrhagic stroke against the background of comorbid HIV infection, who received treatment in hospitals in the Tyumen Region. The study of lipid metabolism parameters was carried out on the Beckman Coulter AU480 analyzer (USA). Blood sampling was carried out on the day of the patients’ admission. The control group consisted of 116 patients. The significance of differences was determined at a two-tailed significance level of p<0.05. Results. The study found lower levels of total cholesterol and low-density lipoproteins in the patients with ischemic stroke against the background of HIV infection. In the patients with hemorrhagic stroke, only a decrease in the level of total cholesterol was noted. Conclusions. The state of the plasma lipid spectrum in patients with HIV infections and ischemic stroke, in comparison with those with hemorrhagic stroke, indicates a lower probability of atherosclerotic genesis of acute vascular cerebrovascular disorder. English version of the article is available at URL:https://panor.ru/articles/changes-in-laboratory-parameters-of-lipid-metabolism-in-hiv-infected-patients-with-cerebral-stroke/80579.html