Abstract
The research is devoted to studying the features of antioxidant protection system in fertile men of various ethnic groups. Studying the features of antioxidant protection processes in the populations of various ethnic origins, living in identical geographical conditions, is of scientific interest. 126 men of reproductive age (84 men of Russian population and 42 men of Buryat population living in Ulan-Ude) were examined. Blood plasma and hemolysate were used as the material for the biochemical research. Modern spectrophotometric, fluorometric and statistical methods were used. The basic indicators of lipid peroxidation, reflecting different stages of oxidation (рrimary,, intermediate, final products] and total antioxidant activity of blood, which characterizes the total activity of inhibitors of radical oxidation, and determining its buffering capacity were studied. We investigated the basic units of antioxidant protection - enzymatic (superoxide dismutase) and non-enzymatic (low molecular weight soluble vitamins retinol and а-tocopherol, oxidized and reduced glutathione). The peculiarities of Ирid peroxidation and antioxidant protection processes in fertile men have significant differences. They can be attributed to the ethnic origin and characterize various degrees of activity of metabolic processes in the surveyed groups. Studying the condition of antioxidant protection system will significantly expand ideas of organism adaptation opportunities to external conditions and will be able to become a basis for effective monitoring of reproductive health.
Highlights
The research is devoted to studying the features of antioxidant protection system in fertile men of various ethnic groups
Studying the features of antioxidant protection processes in the populations of various ethnic origins, living in identical geographical conditions, is of scientific interest. 126 men of reproductive age (84 men of Russian population and 42 men of Buryat population living in Ulan-Ude) were examined
We investigated the basic units of antioxidant protection – enzymatic and non-enzymatic
Summary
В процессе исследования проведен ретроспективный анализ результатов обследования 126 практически здоровых фертильных мужчин репродуктивного возраста бурятской и русской национальностей, проживающих в городе Улан-Удэ, в т. ч. 42 мужчин бурятской и 84 – русской национальности. В процессе исследования проведен ретроспективный анализ результатов обследования 126 практически здоровых фертильных мужчин репродуктивного возраста бурятской и русской национальностей, проживающих в городе Улан-Удэ, в т. Ч. 42 мужчин бурятской и 84 – русской национальности. В качестве материала для биохимических исследований использовали плазму и гемолизат крови. Забор крови проводили из локтевой вены натощак с 8 до 9 часов утра в соответствии с общепринятыми требованиями. В плазме крови флуорометрическим методом регистрировали содержание вторичных продуктов ПОЛ, реагирующих с тиобарбитуровой кислотой (ТБК-АП) С соавт., 1988), содержанию низкомолекулярных антиоксидантов α-токоферола, ретинола С соавт., 1984), восстановленного и окисленного глутатионов (GSH, GSSG) (Hisin P.J., Hilf R., 1976) и активности супероксиддисмутазы (СОД) (Misra H.P., Fridovich I., 1972). Статистический анализ данных проводили с применением программы Statistica 6.1 (StatSoft Inc., США)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
