Зміни показників ротової рідини дітей дошкільного віку з гінгівітом під впливом лікувально-профілактичних заходів

Abstract

Summary. The significant prevalence of inflammatory processes in periodontal tissues of children of different ages indicates insufficient effectiveness of preventive and therapeutic measures. Children of preschool age need special attention in the choice of therapeutic and prophylactic means.The aim of the study – a comparative evaluation of traditional treatment of children aged from 3–5 years with chronic catarrhal gingivitis with therapy with the use of anti-inflammatory gel with neovitin.Materials and Methods. 47 children with chronic catarrhal gingivitis were taken for dispensary observation and divided into groups: the main (23 children) and the comparative (24 children). All children underwent conventional therapy according to the protocols of medical care – basic therapy. In the main group, for a month, pathogenetic agents were used – an anti-inflammatory gel with neovitin, hygiene products were recommended. In the comparative group for local therapy, a 3 % hydrogen peroxide solution was used to rinse the oral cavity (during the first week of treatment) – Rotokan, a therapeutic and prophylactic toothpaste. Control examinations and examination with the definition of the hygienic state of the oral cavity using the hygienic index of Yu. A. Fedorov and V. V. Volodkina, the prevalence and intensity of the inflammatory process in the gums were assessed using the Schiller-Pisarev test and the PMA index, the oral fluid index (formation of oxyradical, urease activity, pH, viscosity, lysozyme content, degree of dysbiosis).Results and Discussion. After the treatment, elimination of gum inflammation in patients of the main group was accompanied by a 2.8-fold decrease in the PMA index; GI – 1.6 times. The reduction in the period of treatment of children was revealed in the application of the proposed treatment regimen. The effectiveness of the treatment was confirmed by a decrease in the formation of oxyradicals immediately after treatment by 15.67 % and 10.98 % (p<0.05), a decrease in urease activity was observed in 8.43 % and 5.47 %; the viscosity of the oral fluid decreased by 54.51 % and 50.51 % (p<0.05), the incidence of dysbiosis decreased by 22.49 % (p<0.05) and 10.36 % in children of the primary and comparative groups, respectively. After 0.5 years, the lysozyme content in the oral fluid of children increased by 21.12 % and 7.09 % (p<0.05), the pH increased by 1.39 % and 0.25 % (p>0.05) in children of the primary and comparative groups, respectively.Conclusions. The use of the proposed therapy with gel with neovitin contributed to the best results of treatment: a decrease in the degree of gingival inflammation by the PMA index by 2.8 times, a decrease in the number of visits to a doctor by 1.1, improvement of the oral fluid of children, and, to a greater extent, six months after the performed treatment.