Клінічна ефективність лікувально-профілактичних заходів при хронічному катаральному гінгівіті

Abstract

Treatment of inflammatory periodontal diseases remains an urgent problem of dentistry as a result of frequent recurrence, inflammation in alveolar bone tissue with periodontal tissue destruction, so developing pathogenetic effects in treating the chronic catarrhal gingivitis is timely.The aim of the study – to conduct the pathogenetic treatment of gingivitis and the assessment of its effectiveness.Materials and Methods. 67 children aged 16–18 years, suffering from chronic catarrhal gingivitis, were taken under clinical supervision and divided into groups: the main (35 children) and the comparative (32 children). All children underwent conventional therapy in accordance with the protocols for the provision of medical care – basic therapy. In the main group, for a month, pathogenetic agents were used: an anti-inflammatory gel with neovitin, hygiene products were recommended. In the comparative group, 3 % hydrogen peroxide solution was used for local therapy, for rinsing of the mouth (during the first week of treatment) – Rotokan, a therapeutic and prophylactic toothpaste.Examination and control examinations were carried out with the hygienic state of the mouth determined by the hygienic index of Green-Vermillion (ОНІ-S), prevalence and intensity of the inflammatory process in the gums with the help of the Schiller-Pisarev test and the PMA index, oral fluid index (content of total glutathione, oxidized and reduced glutathione, glutathione redox index).Results and Discussion. Immediately after the treatment in the main group, the decrease in the PMA index was 2.6 times; GI – in 1.4 times, ONI-S – in 1.7 times. A reduction in the treatment period of adolescents in the application of the proposed therapeutic scheme is established. The content of total glutathione in the main group was significantly higher (p <0.05) than that of the comparator group before treatment (by 12.2 %) and comparing the indicator in 0.5 years (by 8.8 %). In this observation period, the difference between the content of oxidized and reduced glutathione in persons of the main and comparative groups was also significant – 1.8 times and 1.2 times, respectively. In addition, the redox index of glutathione in the main group increased and even exceeded the control group, although there was no significant difference.Conclusion. The use of the proposed therapy with gel with neovitin contributed to the best results of treatment: reducing the degree of inflammation of the gums, the number of visits to the doctor, improving the indices of nonspecific protection in the oral fluid and, to a greater extent, six months after the treatment.