Abstract
<p>The combination of a number of adverse factors as the effect of hypoxic atmosphere, mental work and emotional stress, creates conditions for the development of maladaptive changes in the regulatory systems of the body. changes in autonomic regulation of cardiac cycle of rats under hypoxic atmosphere combined influence and melatonin were studied. The aim of the study was to identify the role of melatonin as factor of biorhythms synchronization in the impact on autonomous regulation of heart rate in young and adult rats with hypoxic incubation environment under conditions of low atmospheric pressure.</p><p>The use of melatonin drug in therapeutic doses in adults, after the completion of puberty, may be useful for the prevention of meteotropic reactions and improve the efficiency of the organism in adverse weather conditions, type III.</p>
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