Autonomous regulation of heart rate in conditions of blocking the beta 1-adrenergic receptors in associative cortex of young rats with hypoxic exposure

Abstract

<p>The literature discusses modulation of beta-adrenergic receptors sensitivity of the cerebral cortex under changed<br />conditions for the functioning of the body. However, very little data on the effect of the hypoxic environment to the<br />sensitivity of beta-adrenergic receptors of the cerebral cortex in a young body, which possible to investigate in<br />experiments on rats. The aim of the experiment was to determine the functional consequences of the exclusion of<br />beta1-adrenergic receptors in the associative cortex in young rats after incubation in hypoxic environment under<br />conditions of low atmospheric pressure. Blocking the beta1-adrenergic receptors in young rat’s associative cortex<br />can significantly offset the regulatory effects on heart rate that occurred during incubation in the hypoxic environment<br />under conditions of low atmospheric pressure. Hypoxic effect in young rats resulted in a significant decrease in<br />sensitivity beta1-adrenergic receptors in the associative cortex.</p>