Abstract
Operative intervention is a strong stress, which creates the prerequisites for both exacerbation of chronic inflammatory processes of the mucous membrane of the stomach and duodenum, and the development of ulcers I erosions in previously conditionally healthy individuals - the so-called “stress-induced changes”.
 The article presents historical recollections of the study of the problem. Also data are given on the incidence of stress-induced changes in the mucous membrane of the upper gastrointestinal tract, both in patients in the intensive care unit in the presence of a critical condition, and in persons undergoing postoperative rehabilitation, according to the results of the world’s largest randomized research.
 Widespread aspects of pathogenesis are highlighted - emphasis on the role of mechanisms of hypoperfusion of internal tissues and the state of acidity of gastric juice as the primary causes of stress-induced changes in the mucous membrane of the stomach. The most informative methods of examination for the detection of erosive-ulcerative changes of the mucous membrane of the digestive tract are presented. Also, the results of studies of various methods of prevention and treatment of changes in the mucous membrane of the upper gastrointestinal tract are presented.
 The problem of stress-induced erosive-ulcerative changes in the mucous membrane of the stomach and duodenum for pediatric surgery for a long time was not paramount. However, with the development of operational technology of treatment, the emergence of new methods to expand the scope of surgical intervention, the relevance of the latter began to grow. In addition, a separate role should be attributed to the development of market relations and the formation of a modern system of financing medical and diagnostic process.
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