Влияние гормонотерапии на уровень половых гормонов женщин с фиброаденомами молочных желез, прооперированных с помощью вакуумной экстракции

Abstract

48 women at the age of 26,5±3,8 with the benign tumors of the mammary glands (fibroadenomas)
 were operated by means of vacuum aspiration with the En‐cor apparatus (made in the USA) under the
 ultrasound control. The tactics of the surgery satisfied the requirements (standards) accepted in Russia. In
 the core group (II, 20 patients) low‐dose monophasic combination oral contraceptives with the ethinylastradicol
 as an active ingredient at a dose of 20 mcg were prescribed for six months beginning with the 1st day of
 the menstrual cycle (period) which followed the operation. In the group of comparison (22 patients) the
 hormone‐therapy during the post‐operative period wasn’t carried out. The observing time after the operation
 lasted in average two and a half years (the maximal duration was 3,2 years, the minimal one – 2,1 years).
 For the two check points the date of the access and the sixth month after the adenomammectomy were chosen.
 During this time the laboratory, breast ultrasound and the clinical forms of control of the condition of
 the mammary gland and of the hormonal background were carried out. The investigation revealed the normalization
 of the background of the female and the male sex hormones after the adenomammectomy by
 means of the aspiration method. It was characteristic for the women to whom the hormone‐therapy after the
 adenomammectomy was prescribed that the changes with them were maximal. Apart from the normalization
 of the general hormonal background of these women there were also some signs of a significant reduction
 in the risk of recurrence and the development of new fibroadenoma of breast.