ОЦЕНКА ЭФФЕКТИВНОСТИ ПРОБИОТИКА, ПОДВЕРГНУТОГО СОЧЕТАННОМУ ВОЗДЕЙСТВИЮ ТЯЖЕЛЫХ ЧАСТИЦ И ГИПОМАГНИТНОЙ СРЕДЫ, В ЭКСПЕРИМЕНТЕ С ВЫВЕШИВАНИЕМ КРЫС

Abstract

A probiotic food subjected to a combined exposure to hypomagnetism and heavy charged particles was tested for the ability to counteract the negative effects of these spaceflight factors. The experiment was conducted with 36 male Wistar rats. The experimental group of animals (n=18) was tail-suspended for 21 days in order to experience a modeled hypogravity. Their controls were held in individual cages without suspension. Both groups were divided into 3 subgroups depending on which supplement they consumed, i.e. placebo, a probiotic food that had been or had not been exposed to proton radiation and hypomagnetism. As a result, it was established that suspension, as a stressor, causes reductions in the majority of intestinal protective microflora and that the preventive food levels the negative changes significantly. The number of lactobacilli in the suspended group fed with the probiotic food exposed to radiation and hypomagnetism remained unchanged throughout the experiment. This fact points to the stabilizing effect of the food on intestinal microflora. Effectiveness of the exposed food was close to that of usual.