ФИТОХИМИЧЕСКИЙ АНАЛИЗ, РАЗРАБОТКА СОСТАВА И ТЕХНОЛОГИИ КАРАНДАШЕЙ С ЭФИРНЫМ МАСЛОМ ЛИСТЬЕВ МЯТЫ ВОДНОЙ, ПРОИЗРАСТАЮЩЕЙ НА СЕВЕРНОМ КАВКАЗЕ

Abstract

The leaves of water mint growing in the Northern Caucasus were chosen as an object of research. Earlier authenticity of water mint on external and anatomo-diagnostic signs with the purpose of distinction from close species was defined. Based on the results of qualitative reactions and quantitative determination (steam distillation method) in the leaves of water mint was detected essential oil, the content of which was 1,92%. The method of ascending chromatography on paper identified flavonoids: rutin, luteolin, hyperoside. The presence of flavonoids in the raw material was confirmed by cyanidine test (by pink staining) and the formation of a yellow-green complex (with a solution of aluminum chloride (III) 2% alcohol). The spectrophotometric method determined the content of the sum of flavonoids in terms of luteolin, which was 0,72±0,05%. The method of approximate-quantitative spectral analysis analyzed the content of chemical elements from the place of preparation of leaves of water mint in Chegemsky area of KBR. The research revealed 7 trace elements as additional sources possessing antiseptic; analgesic; antipyretic; anti-inflammatory; wound-healing, etc. properties. The optimal bases (beeswax, cocoa butter, paraffin, PEO-4000, PEO-400, tween-80, lanolin, peach oil) for medical pencils with aqueous mint essential oil were selected experimentally. For this purpose, 5 compositions of pencils with a model concentration of essential oil of 2% were selected. The technology of making pencils by pouring method was developed. The estimation of smearing and sticking ability of pencils was carried out. It is established, that the best smearing and sticking ability possesses a pencil of composition №5 which has been chosen as optimum for the further researches.