Abstract
Coronary artery disease (CAD) is one of the leading causes of mortality and morbidity worldwide, requiring modern approaches to diagnosis and treatment. Coronary angiography has long been considered the «gold standard» for diagnosing CAD; however, this method does not account for the functional significance of stenoses. The 2024 European Society of Cardiology (ESC) guidelines emphasize the importance of intravascular imaging and coronary physiology assessment as key diagnostic methods. This article describes a clinical case of a patient in whom coronary angiography revealed suspected destabilization of an atherosclerotic plaque, leading to the development of acute coronary syndrome. Through the use of modern technologies, including fractional flow reserve (FFR), diastolic hyperemia-free ratio (DFR) and intravascular ultrasound (IVUS), the key pathophysiological stages of plaque destabilization were documented, successful coronary stenting was performed, and myocardial blood flow was restored. This clinical case highlights the importance of innovative approaches to the diagnosis and treatment of vulnerable plaques and confirms their relevance in contemporary cardiology practice.
Published Version
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