Abstract
WHO experts have determined that medical abortion and vacuum aspiration are currently safe methods of terminating an unintended pregnancy in the first trimester. Aim - to conduct a comparative analysis of the clinical effectiveness and safety of modern methods of early artificial abortions. Materials and methods. An analysis of early and late complications of early abortion was carried out in 54 women with medical abortion using mifepristone and misoprostol (group I) and 65 respondents after abortion by vacuum aspiration (group II). Statistical data processing was carried out using the SPSS 21 program. Results. The frequency of fetal egg retention, pregnancy progression, abnormal uterine bleeding, and endometrial polyps was significantly higher after medical abortion, and endometritis - after vacuum aspiration. Women who underwent medical abortion compared to termination of pregnancy by vacuum aspiration have a 2.3 and 3.6 times lower risk of placental complications and the threat of termination of future pregnancy (odds ratio (OR): 0.28; 95% confidence interval (95% CI): 0.12-0.64 and OR: 0.24; 95% CI: 0.06-0.88), as well as cesarean delivery (OR: 0.34; 95% CI: 0.14-0.84). Conclusions. The effectiveness of the medical method of early termination of pregnancy was 90.7%, vacuum aspiration - 98.5%, which is a relatively safe alternative to surgical abortion. This study did not involve any experiments on animals or humans. No conflict of interests was declared by the authors.
Published Version
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