Сравнение эффективности внутрисуставного введения препаратов гиалуроновой кислоты с разной кратностью введения после артроскопических операций на коленном суставе

Abstract

This study was conducted to evaluate the efficacy of various hyaluronic acid (HA) preparations in patients with knee joint injuries in the postoperative period after knee arthroscopy. Ninety patients with grade I–II gonarthrosis and concomitant meniscus damage who underwent knee arthroscopy were included in the study. Patients were divided into three groups of 30 patients: in the 1st group no HA preparations were administered, in the 2nd group threefold administration of HA with the concentration of 1.6% was performed with the volume of 2 ml, in the 3rd group a single injection of HA with the concentration of 2.2% mixed with mannitol was performed with the total volume of 5 ml. After 1, 6 and 12 months, the dynamics of the mean score on the visual analog scale (VAS) of pain, WOMAC index and Leken's algo-functional index were evaluated. According to the results of observation after 6 and 12 months, the most pronounced dynamics of pain syndrome intensity reduction was observed in groups 2 and 3, where HA preparations were administered after knee arthroscopy. No statistically significant differences in the efficacy of the compared HA preparations were found. According to the results of observation after 6 and 12 months, the most pronounced dynamics of pain syndrome intensity reduction was observed in groups 2 and 3, where HA preparations were used after knee arthroscopy. No statistically significant differences in the efficacy of the compared HA preparations were revealed. HA administration after arthroscopic lavage causes persistent regression of pain syndrome and improvement of functional status of the knee joint.