The maternal gene products control the initial stages of embryo development in all animals. The role of controlling embryogenesis is taken up by the zygotic genome at some point after fertilization. This paper seeks to shed light on research on the effect of the zinc-finger protein Zelda on the expression of bnk in fruit flies. The zinc-finger protein Zelda (Zld) is a transcriptional activator of the early zygotic genome and plays an important role in early embryonic development. (Liang,2008) This paper mainly demonstrates the influence of Zld on the bnk, which encodes a kind of protein that controls the actinic organization and the time of cellular basal closure. In the absence of Zelda, the expression of bnk has subtle changes. This work highlights the importance of the zinc-finger protein Zelda in the expression of the bnk in fruit flies and also details the methodology followed in the research on the bnk expression in fruit flies, the results, and the conclusions drawn from the research work, showing the importance of Zld to bnk, especially in early embryonic development stages. The significance of this research is to open potential avenues for research on identifying genes whose expression has been influenced to some extent by Zelda. Also, understanding the effect of Zelda on bnk expression can aid in the manipulation of the two variables to establish a functional interaction.