Zamzam Water Research Articles

Investigate the utilization of novel natural photosensitizers for the performance of dye-sensitized solar cells (DSSCs)

Dye-sensitized solar cells (DSSCs) offer a promising route for sustainable energy conversion, with natural photosensitizers emerging as attractive alternatives to conventional synthetic dyes due to their abundant resources, cost-effectiveness, and eco-friendly materials. However, the efficiency of DSSC utilizing natural photosensitizer remains low. In this study, we investigate the utilization of novel natural photosensitizers extracted from gambier leaves, gambier branches, cinnamon, and petiole of tectona leaves, which contain flavonoids/tannins, chlorophyll, and anthocyanins, aiming to achieve high-performance DSSCs. Five different solvents—ethanol, isopropanol, distilled water, methanol, and Zamzam water—are explored to optimize the extraction process of the natural dyes. The doctor blade technique is employed to coat TiO2 nanomaterials onto ITO glass substrates. UV–Vis spectrophotometry and FTIR spectroscopy are used to characterize the optical properties and structural composition of the dyes, revealing that flavonoid/tannin groups are the primary compounds responsible for light harvesting. The DSSC performance is evaluated under a 30 W lamp, adjusted to light intensity of 10 mW/cm2. As a result, the DSSCs using gambier leaf extract as photosensitizer demonstrate the highest recorded efficiency of 4.71 %, with a Jsc of 2.95 mAcm−2 and a Voc of 0.64 V. These findings contribute to advancing DSSC technology by leveraging the potential of natural photosensitizers for sustainable energy conversion applications.

Prophetic Medicine in the Context of Middle Eastern Culture: A Concept Analysis.

Background: Prophetic Medicine, integral to healthcare in Muslim-majority regions, particularly the Middle East and North Africa, is often underexplored in existing literature. Purpose: This concept analysis sought to explore the concept of Prophetic Medicine by delineating its attributes, antecedents, and consequences in order to augment healthcare providers' comprehension of Prophetic Medicine. It also seeks to enhance interdisciplinary dialogue, thereby enriching the integration of traditional healing modalities in modern medical practices. Methods: Walker and Avant's method was used to conduct the concept analysis by reviewing published literature on the concept. Results: The analysis identified the core attributes of Prophetic Medicine, such as Black Seeds, Dates, Miswak, Wet cupping, and Zamzam water, and explored cultural, spiritual, and practical underpinnings of these practices. Antecedents such as cultural background, spiritual beliefs, basic knowledge, lower cost, perceived safety, efficacy, simple techniques, and dissatisfaction with allopathic therapy were identified. The consequences of these practices include the multifaceted impact of Prophetic Medicine, highlighting the relationship between these traditional practices and health outcomes. Implications for Practice: This concept analysis underscores the significance of recognizing these aspects of Prophetic Medicine for healthcare providers to effectively integrate Prophetic Medicine into practice, aiming for favorable patient outcomes and fostering a more inclusive, culturally sensitive healthcare environment.

The Meaning of Symbols in The Peucicap Aneuk Procession in Aceh: A Semiotic Study

The Peucicap Aneuk tradition is part of past culture with historical value. In its implementation there are religious symbols that have their own meaning. The approach used in this research is semiotic theory to read and understand the meaning of the symbols used by the people of Aceh during the implementation of the Peucicap Aneuk procession. with descriptive qualitative research design. primary data of this research comes from field observations of the Peucicap Aneuk procession and secondary data comes from journals, books, and ancient Acehnese manuscripts. This research showed that, in general, the Acehnese people perform the Peucicap Aneuk procession in the morning on the 7th (seventh) day after a mother gives birth to her child. When the peucicap ritual is carried out, there are 17 (seventeen) symbols, namely rice and paddy, sticky rice, Tumpo, On Peusijuek, free-range chicken egg yolk, rice kneaded into porridge, honey, Zam-Zam water, fruits, chicken thighs, chicken liver, turmeric, salt, sugar, coconut, mirror, Quran. In the Peucicap Aneuk procession, this article confirms the expectations of every parent for their children through the representation of cultural symbols. This article shows that there are several relations between the role of these symbols and the spirit of the community to preserve this culture in line with Islamic values.

Histological and CBCT evaluation of Zamzam water (gel) versus topical fluoride in remineralization potential of induced enamel caries (In vitro study)

Histological and CBCT evaluation of Zamzam water (gel) versus topical fluoride in remineralization potential of induced enamel caries (In vitro study)

Zamzam Water Surpasses Global Standards in Quality and Mineral Content

This study investigates the physical, chemical, and bacteriological properties of Zamzam tap water and two popular bottled waters, "Rounaq" and "Naba' Al- Rayan," in Diyala Governorate. Conducted at Al-Rafidain University College and the Central Public Health Laboratory in Baghdad, the research analyzes taste, odor, color, pH, essential minerals, and bacterial contamination. Findings indicate that Zamzam water excels in sensory qualities and contains beneficial minerals like potassium and magnesium within safe limits, with no bacterial contamination detected. These results affirm Zamzam's superior quality and underline the necessity for regular quality checks of bottled waters to ensure public health safety. Highlights: Superior Sensory Qualities: Zamzam water was notably superior in taste, odor, and color compared to the other bottled waters tested. Mineral Content and Safety: All water samples contained essential minerals like potassium and magnesium within safe limits, confirming their nutritional value and compliance with health standards. Bacterial Purity: No bacterial or pathogenic contamination was detected in any of the water samples, ensuring their safety for consumption. Keywords: Zamzam Water, Bottled Water Quality, Mineral Content, Bacteriological Safety, Sensory Properties

Zamzam Water Mitigates Cardiac Toxicity Risk through Modulation of GUT Microbiota and the Renin-angiotensin System.

Cardiovascular diseases (CVDs) continue to exert a substantial global influence in specific areas due to population growth, aging, microbiota, and genetic/environmental factors. Drinking water has a strong impact on the health of an individual. Further, emerging evidence has highlighted the therapeutic potential and benefits of Zamzam water (Zam). We investigated the influence of Zam on doxorubicin-induced cardiac toxicity, elucidating its consequential effects on GUT microbiota dysbiosis and hepatic and renal functions. Male rats were categorized into four groups: Group 1 as Normal control (NC), Group 2 as Zamzam control (ZC), Group 3 Disease control (DC) and Group 4 as Therapeutic control (DZ) treated with Zam against doxorubicin-induced disease at a dose of 1mg/kg boy weight) intraperitoneally (i.p). Significant dysbiosis in the composition of GM was observed in the DC group along with a significant decrease (p < 0.05) in serum levels of Zinc, interleukin-10 (IL-10), IL-6 and Angiotensin II (Ang II), while C-reactive protein (CRP), fibrinogen, and CKMB increased significantly (restoration of Zinc ions (0.72 ± 0.07 mcg/mL) compared to NC. Treatment with Zamzam exhibited a marked abundance of 18-times to 72% in Romboutsia, a genus of firmicutes, along with lowering of Proteobacteria in DZ followed by significant restoration of Zinc ions (0.72 ± 0.07 mcg/mL), significant (p ˂ 0.05) reduction in CRP (7.22 ± 0.39 mg/dL), CKMB (118.8 ± 1.02 U/L) and Fibrinogen (3.18 ± 0.16 mg/dL), significant (p < 0.05) increase in IL-10 (7.22 ± 0.84 pg/mL) and IL-6 (7.18 ± 0.40 pg/ml), restoration of Ang II (18.62 ± 0.50 nmol/mL/min), marked increase in renin with normal myocyte architecture and tissue orientation of kidney, and restoration of histological architecture of hepatocyte. Zam treatment mitigated cardiac toxicity risk through the modulation of GUT microbiota and the renin-angiotensin system and tissue histology effectively.

A study on the effect of Zamzam water on the germination and growth of Jasminum sambac

This paper seeks to investigate the role of Zamzam water in enhancing the germination and post-germination growth of Jasminum sambac. Zamzam water contains many mineral and chemical properties that have been previously tested as a model for supporting fertilization efforts in agricultural production. Seeds were planted for Zamzam water with a distilled water serving as a control to tabulate the rate of germination and the length of emergent seedlings. Zamzam’s role in supporting the growth of the Jasminum sambac was displayed with statistically significant differences being present, suggesting potential for further research into Zamzam’s potential as an agent for plant growth.

Muslim pilgrims’ knowledge, attitudes, and practices regarding complementary and alternative medicine (CAM); a study conducted during Hajj season

Complementary and alternative medicine (CAM) has attracted much interest, and its prevalence in both developed and developing countries has increased. During the Hajj season, millions of Muslims from many different countries travel to Makkah for the pilgrimage. In dealing with health issues during the holy season, many pilgrims prefer to self-medicate with traditional remedies instead of visiting medical practitioners, which could affect the efforts of state healthcare organizations to maintain overall public health during this mass gathering. This study aims to gauge the prevalence of CAM use during Hajj, and to assess pilgrims’ beliefs and knowledge of CAM therapies, with particular reference to products available in Makkah. A cross-sectional survey was conducted in several camps and hotels occupied by Hajj pilgrims in Makkah, during Hajj 2023. CAM modalities were used by 68.8 % of the study participants during the Hajj season. There were almost equal numbers of men (53.7 %) and women (46.3 %) participants, with 88 % of the CAM users being non-Saudi and only 12 % Saudi. The majority of the CAM users belonged to two age groups, the 31–40 year group (29.9 %) and the 41–50 year group (34.5 %). The most frequent self-practice therapies were religious prayer/rituals (30.2 %), and the most popular practitioner therapies was herbal treatments (12.3 %). The most common source of CAM-related information was family/friends (29.2 %), for improving well-being reason (25.8 %). More than half of the participants (56.8 %) strongly believed that CAM therapies have the potential to cure disease, although they were unaware of possible interactions between CAM and conventional drugs (76.7 %). More than half of the participants (57.8 %) did not disclose their CAM usage to healthcare practitioners. Half of the sample said they used CAMs during Hajj because of the common belief that therapeutic products from the holy city of Makkah, such as Zamzam water, are more effective. In conclusion, CAM therapies are commonly used by Hajj pilgrims as they are presumed to be natural and therefore safe, raising concerns about the potential risks of relying on CAM without adequate consultation with healthcare providers or awareness of potential interactions between prescription drugs and CAM treatments.

Biochemical Study of Zamzam Water According to Cities Water

Biochemical Study of Zamzam Water According to Cities Water

Exploring Integrative Approaches: Insights Into Complementary Medicine Practices Among Breast Cancer Survivors in Saudi Arabia.

Complementary and integrative medicine (CAM) is a prevalent approach often used with conventional medical practices The study aims to understand the factors influencing breast cancer (BC) survivors' decisions regarding CAM therapy and the drivers behind their use. This research was conducted at an academic hospital in Saudi Arabia. The study used cross-sectional research with a questionnaire. Participants were enrolled in the study through BC survivors' groups on WhatsApp. Individuals who were actively following up at the clinic were also interviewed. Informed consent was obtained. The study surveyed 211 BC survivors, aged 34-49 (50.2%), who had undergone surgery (93.4%), hormonal therapy (66.4%), and chemotherapy (87.7%). Less than half (44.5%) had chronic conditions such as diabetes and hypertension. CAM users were 43.6%. The most used CAM modalities were Zamzam water, honey, and water read-upon Quran. A significant motivator for CAM use was to boost the immune system. More than half of patients used less than 100 SAR per month on CAM modalities. Exactly 80.4% of CAM users perceived benefits from CAM use. Predictors of CAM use included higher family monthly income, radiation therapy, and being diagnosed from 1 to 5 years. BC survivors without medical conditions after diagnosis were less likely to use CAM. The study highlights the prevalence, predictive factors, motivations, and perceived benefits of CAM use among BC survivors in Saudi Arabia, emphasizing the need for understanding and integration into cancer care plans and the need for further research on CAM safety and efficacy.

The Effect of Zamzam Water and ProShieldR Varnish on Microhardness of Eroded Primary Enamel Teeth Induced by Ironplus Syrup: An In Vitro Study

The Effect of Zamzam Water and ProShieldR Varnish on Microhardness of Eroded Primary Enamel Teeth Induced by Ironplus Syrup: An In Vitro Study

People's Knowledge and Attitudes About Factors That Can Impact Wound Healing in the Eastern Province, Saudi Arabia.

Background Wounds, ranging from acute to chronic, demand timely intervention to prevent complications. Infections can impede healing, leading to sepsis. Chronic wounds impact society, causing limitations in mobility and social exclusion. Early identification of infections is crucial for effective treatment, reducing unnecessary antibiotic use, and improving patient outcomes. Methodology This cross-sectional study was conducted from June to October 2023 in Saudi Arabia using a self-administered online questionnaire to assess wound healing knowledge and attitudes. Convenient random sampling via social media was employed to collect data. Data analysis was performed using SPSS version 23 (IBM Corp., Armonk, NY, USA). Results Our study predominantly featured female (67.1%), Saudi (94.8%), aged 18-25 years (42.0%), and married (51.1%) participants. Chronic illnesses were prevalent in 24.2%, with heart disease (5.7%) and hypertension (4.5%) being notable. Burn injuries (27.4%) and upper extremity wounds (40.9%) were common, prompting immediate medical care (54.1%). Internet sources (22.6%) and relatives/friends (18.4%) were key for wound care information. Participants displayed solid awareness of wound-related factors, with notable misconceptions regarding Zamzam water (44.4%) and coffee beans (39.3%). Participants prioritized stopping bleeding (41.1%) and using wound patches (42.1%) for home injuries. Age group, education, marital status, and occupation impacted knowledge about wound healing. Conclusions Our study highlights key demographics, prevalent chronic illnesses, common wound types, and crucial sources of wound care information. Participants' awareness, coupled with notable misconceptions, emphasizes the importance of tailored education. Factors such as age, education, marital status, and occupation impact knowledge about wound healing.

Accurate computer simulation phase-shifting digital interferometry for measurement of the optical properties of Zamzam water in the visible spectrum Nasser A. Moustafa1,2, Hasan Assaedi2, Thamer H. Albaqami2 1Physics Department, Faculty of Science, H

Accurate computer simulation phase-shifting digital interferometry for measurement of the optical properties of Zamzam water in the visible spectrum Nasser A. Moustafa1,2, Hasan Assaedi2, Thamer H. Albaqami2 1Physics Department, Faculty of Science, H

Perspective of adults in Saudi Arabia toward complementary and alternative medicine use for autism spectrum disorder: a cross-sectional study

BackgroundAutism Spectrum Disorder (ASD) is a high-prevalence neurodevelopmental disorder characterized by communicational, social, and behavioral challenges. Complementary and alternative medicine (CAM) is a group of practices and products that fall outside the realm of conventional medicine practiced worldwide. Traditional CAM is a health practice that comes from a particular culture, such as the use of Zamzam water and black seeds in Saudi Arabia. CAM comprises widely utilized practices in Saudi Arabia for children of various ages and adults. In many cases, CAM is used to treat ASD. The aim of this study is to investigate the perspectives of adults in Saudi Arabia toward CAM for treating ASD.MethodsA cross-sectional study was conducted by distributing an online questionnaire to adults in different regions of Saudi Arabia.ResultsA total of 4,311 adults participated in this study; 66.8% were females and 33.2% were male. Half of the participants reported that they knew about ASD (54.7%). More than half of the participants indicated that CAM—including art therapy (69.0%), physical exercise (67.0%), and limiting the use of electronic (55.4%)—could help in ASD management. Around half of the respondents indicated a belief that traditional treatment cannot help in treating ASD (53.9%). Only 20.0% of the respondents thought that ASD could be entirely treated using CAM therapies. The most common source of knowledge about CAM was social media and the internet (58.6%).ConclusionsThe majority of participants in this study did not believe that ASD could be treated entirely using CAM. In addition, fewer than half of the participants believed that CAM therapies could improve different aspects of ASD, such as behavioral issues. The study highlighted the need for awareness among residents of Saudi Arabia regarding specific treatments for ASD.

Anxiolytic and antidepressant like effects of Zamzam water in STZ-induced diabetic rats, targeting oxidative stress, neuroinflammation, BDNF/ERK/CREP pathway with modulation of hypothalamo-pituitary-adrenal axis.

Recent studies have reported a strong relationship between diabetes and anxiety- and depression-like behaviors; however, there is a lack of information on the underlying pathophysiology. Alkaline Zamzam water (ZW), which is rich in several trace elements, has neuroprotective properties. This study aimed to investigate the anxiolytic and antidepressant effects of ZW against diabetes-induced behavioral changes and shed light on the possible underlying mechanisms. Forty-eight rats were divided into four experimental groups (n = 12): group I (control group), group II (Zamzam water group), group III (diabetic group), and group IV (diabetic + Zamzam water group). Diabetes was induced by an intraperitoneal injection of 60 mg/kg streptozotocin (STZ). At the end of the experiment, the forced swimming test (FST) was used to assess depression-like effects. The elevated plus maze test (EPMT) and open field test (OFT) were performed to evaluate anxiety-like behavior. Blood levels of the hypothalamic-pituitary-adrenal (HPA) axis were measured, and prefrontal cortex and hippocampal tissue samples were removed for histological, immunohistochemical, ELISA, and Q-PCR analyses. ZW significantly decreased the immobility time in the FST, indicating an antidepressant effect (p < 0.001). Additionally, ZW significantly improved the OFT and open field entry (OFE) percentages in the EPMT, increasing center crossing and decreasing grooming and fecal boli in the OFT. This indicated an anxiolytic-like effect in diabetic rats with histological improvement. Interestingly, ZW significantly increased prefrontal cortical and hippocampal levels of antioxidant enzymes and the Nrf2/HO-1 pathway. It also modulated the HPA axis by increasing cortisol and corticotropin-releasing hormone (CRH) levels, with a decrease in ACTH and an increase in monoamine neurotransmitters. Furthermore, diabetic rats that received ZW showed a decrease in the inflammatory markers TNF-α and GFAP by immunohistochemistry and in the mRNA levels of NFκB, IL-1β, and IL6. In addition, ZW downregulated the expression of the BDNF/ERK2/CREP pathway. Our results suggested a neuroprotective effect of ZW against diabetes-induced anxiety- and depression-like behaviors and explored the underlying mechanisms. These findings suggest a promising therapeutic strategy for patients with diabetes who experience anxiety and depression.

Analisis Materi Pendidikan Agama Islam pada Film Animasi Nussa dan Rarra

This research is backgrounded by phenomena found in the field. This phenomenon is obtained by technological advances, so educators as one of the elements of educational success must take advantage of alternative audio-video learning media that have educational value, such as the animated films Nussa and Rarra. Answering parents' concerns about the lack of television shows that have educational value.The research method used is qualitatively categorized into (library research), using a pragmatic approach. This type of research is a semiotic analysis developed by Charles Sanders Pierce. Data collection techniques use documentation methods. Then a descriptive presentation is carried out, namely by providing a detailed description and interpretation and description related to the data that has been collected. The results of this study show that first, there is Islamic religious education material Al-Qur'an-Hadith regarding the learning of hadith to demand guaranteed knowledge of heaven, 'Aqidah; pray only to Allah Almighty, and Morals; Say hello and please others in the episode Rarra: Dijamin Surga. Second, there are Islamic religious education materials 'Aqidah; give thanks, Morals; reprehensible conduct and Fiqh; the right way to pray in the episode Nussa: Alhamdulillah Terkabul. Third, there are Islamic Moral education materials; adab advises and takes responsibility on the episode Rarra: Adab Menasihati. Fourth, there are Islamic Moral education materials; adab enter into the room of others and Fiqh; compulsory dawn prayer on episode Nussa: Sholat itu Wajib. Fifth, there are Islamic Fiqh education materials; Kaaba is the mecca of prayer, Hajj Umrah and prayer before drinking zam-zam water, Tarikh; the history of the Kaaba, as well as the Qur'an-Hadith; Hadith learning from Hajar Aswad in the episode Nussa: Mengenal Ka’bah.

The prevalence and pattern of complementary and alternative medicine use among cancer patients in a tertiary oncology center: a cross-sectional study.

Complementary and alternative medicine (CAM) is widely used nationally and internationally for multiple medical conditions, including different stages of cancer. It is used by the patients for multiple purposes, including to cure diseases or resolve symptoms, as patients have the misconception that natural remedies are safer than radiotherapy and chemotherapy. The aim of this research is to investigate the prevalence, pattern, and purpose of CAM use by cancer patients at Princess Noorah Oncology Center (PNOC), King Abdulaziz Medical City, in Jeddah (KAMC-JD). This was a cross-sectional study that examined 293 patients (selected through random computerized sampling) who were seen at PNOC during the study period. To be eligible for the study, participants had to be cancer patients over the age of 18 who were seen at PNOC. The authors excluded patients who had privacy requests or did not fit our inclusion criteria. Of the sample, 52.9% [95% confidence interval (CI), 47.0-58.7] used CAM. Only 5.8% of patients delayed their medical treatment to use CAM. A significantly higher proportion of females used CAM than males (61.8% vs. 40.0%, P<0.001). The most common types of CAM were Zamzam water (67.7%), Quran recitation (42.6%), water read upon Quran (41.3%), and black seed (Nigella sativa) (41.3%). The most frequently reported reasons for CAM use were to treat cancer (53.5%), increase immunity (34.2%), and religious beliefs (23.9%). Generally, 57.4% of CAM users felt improvement with CAM modalities. In conclusion, more than 50% of our sample used CAM; 5.8% of patients delayed the medical treatment to use CAM. The most common type of CAM was Zamzam water, and the most frequently reported reason for CAM use was to treat cancer. Of CAM users, 57.4% felt improvement with CAM modalities. Further studies that involve qualitative designs and include a more diverse sample are recommended in the Kingdom of Saudi Arabia to understand CAM utilization patterns.

Novel Insights about Synergistic Effect of Zamzam Water with SGL2 Inhibitors on Wound Healing in STZ-Induced Diabetic Rats: The Role of anti-Inflammatory and Proangiogenic Effects

Background: Hyperglycemia usually impairs wound healing by dysregulating the inflammatory response and angiogenesis. This study aimed to examine the synergistic effect of dapagliflozin and Zamzam water (ZW) on the healing of diabetic wounds and to explore their anti-inflammatory and proangiogenic effects. Materials and methods: A full-thickness excisional wound was made on the backs of all groups after two weeks of diabetes induction. Forty rats were divided into five groups, with eight rats per group; Group 1: Control non-diabetic rats; Group II: Untreated diabetic rats; Group III: Diabetic rats drinking ZW; Group IV: Diabetic rats receiving an oral dose of 1 mg/kg dapagliflozin; and Group V: Received both dapagliflozin and ZW. The healing of diabetic wounds was assessed by measuring wound closure, oxidative stress markers, immunohistochemical staining of NF-βB, VEGF, CD34, CD45, Ki-67, and eNOS, gene expression of MMP-9, TGF-β1, EGF-b1, FGF, and Col1A1, protein levels of TNFα, IL-1β, IL6, Ang II, and HIF-1α by ELISA assay, and histological examination with H & E and Masson’s trichrome. Combined treatment with dapagliflozin and ZW significantly (p < 0.05) enhanced the wound closure and antioxidant enzyme level, with apparent histological improvement, and shortened the inflammatory stage of the diabetic wound by decreasing the level of inflammatory markers NF-κB, TNF-α, IL-1β, IL6, and CD45. Therefore, it improved angiogenesis markers VEGF, CD34, eNOS, EGF-β1, FGF, Ang II, and HIF-1α, increasing Ki-67 cellular proliferation. Moreover, it enhanced the remodeling stage by increasing MMP-2, TGF-β1, and Col1A1 levels compared to diabetic rats.

"Sacred Zamzam Water: Metallic Profile and Health Benefits"

"Sacred Zamzam Water: Metallic Profile and Health Benefits"

Al-Hijamah (Prophetic Wet Cupping Therapy) is a Novel Adjuvant Treatment for Viral Hepatitis That Excretes Viral Particles and Excess Ferritin Percutaneously, Synergizes Pharmacotherapy, Enhances Antiviral Immunity and Helps Better HCC Prevention and Treatment: A Novel Evidence-Based Combination with Prophetic Medicine Remedies.

Viral hepatitis progresses to liver cirrhosis and HCC. Several challenges are facing Sovaldi treatment to viral C hepatitis, eg, viral resistance, difficulty to treat all genotypes, and inability to access treatments in low-income countries. Also, current treatments to Hepatitis B are still challenging. Ideal treatments to viral hepatitis should decrease the viral load, enhance antiviral immunity and repair the viruses-induced tissue damage. That is still beyond reach. High serum ferritin in viral hepatitis correlates with chronicity, increased necro-inflammation, hepatotoxicity, progression to cirrhosis, progression to HCC, unresponsiveness to treatments and viremia. Previously, Al-hijamah (wet cupping therapy of prophetic medicine) significantly cleared thalassemic children of causative pathological substances (CPS), eg, excess ferritin, free radicals and serum lipids. Moreover, Al-hijamah significantly increased the antioxidant power and potentiated the natural antiviral immunity, eg, increasing CD4 count, CD8 count and CD4/CD8 ratio. Prophet Muhammad peace be upon him said: "If there is a benenvolence (benefit) in any of your medicines, benefit will be in shrtat mihjam (Al-hijamah), honey drink, and a stinge of fire compatible with disease and I do not like to cauterize". Likewise, the author suggests Al-hijamah as a novel promising adjuvant treatment for viral hepatitis (B and C) for percutaneous excretion of CPS as hepatitis viral particles, excess ferritin, inflammatory mediators, free radicals, and antigen-antibody complexes. Published reports proved that Al-hijamah exerted tissue-protective effects, and cleared blood through the fenestrated skin capillaries in a pressure-dependent and size-dependent manner (a kidney-like manner). That collectively may decrease the viral load for better HCC prevention and supports the evidence-based Taibah theory (Taibah mechanism). Same therapeutic benefits apply to other viral illnesses as AIDS. Even after HCC development, Al-hijamah is quite mandatory for excretion and clearance of CPS that favor malignancy, eg, lactate (Warburg effect), growth factors, metalloproteinases, and others. Al-hijamah-induced immune potentiation benefits HCC patients. Combining Al-hijamah with other natural antioxidant remedies of prophetic medicine, eg, nigella sativa, costus, natural honey, Zamzam water and others will maximize the therapeutic benefits. In conclusion, Al-hijamah and other prophetic medicine remedies are recommended adjuvants to current pharmacological treatments to viral hepatitis and HCC.