ABSTRACT Gay-specific mobile dating apps such as Grindr are popular among young gay, bisexual, and other men who have sex with men (GBMSM) worldwide. However, how the use of these apps differs between regions is underexplored. In this study, we drew on the uses and gratifications literature and cross-cultural studies to examine how cultural-psychological differences (sensation seeking and communication apprehension) and social acceptance of same-sex relationships are associated with the motives for using gay dating apps in three East Asian cities. Using a sample of 18–34-year-old GBMSM (217 participants from Hong Kong, 330 from Taipei, and 175 from Osaka), we found that the Taiwanese participants scored higher than their Japanese counterparts on almost all motives. Sensation seeking was positively associated with using gay dating apps for casual sex, self-worth validation, and thrill of excitement in both Taipei and Osaka. Communication apprehension was positively associated with using the apps for ease of communication in all three cities. Social acceptance of same-sex relationships had positive relationships with using the apps for love in Hong Kong and casual sex in Taipei but negative relationships with other motives in Taipei and Osaka. These inconsistent relationships between the variables across the three cities point to the importance of cultural and regional specificity in predicting gay dating app use motives.