While many studies have discussed the effectiveness of interventions using different yoga techniques and teachings with various populations, there has been less research on the effectiveness of yoga therapy. Viniyoga therapists utilize the principles of Viniyoga, a type of yoga developed by Krishnamacharya, to provide therapeutic yogic interventions to individual clients in order to improve functioning and relieve suffering. This qualitative study conducted interviews with fourteen Viniyoga trained yoga therapists to understand the impact of Viniyoga therapy on state change. State change is defined as either a physical or psychological change that improved well-being, ameliorated suffering, or increased insight for the client. The researchers used an in-depth semi-structured interview while utilizing open-ended questioning. A definition of Viniyoga Therapy was developed, and distinctions were made between yoga therapists and yoga teachers. Subjects interviewed discussed the results of their interventions using the 5-dimensional pañcamaya model, which considers a client’s structure, physiology, mind, personality, and emotions. Viniyoga therapists interviewed drew from their own observations, as well as clients’ self-reported data. Results were analyzed using NVivo software and based on Interpretive Phenomenological Analysis principles. Five important themes emerged: 1) Viniyoga empowers clients to participate in their own process of state change by training their self-observation skills and providing tools for influencing their state 2) Intentionally engineered experiences are the tools of Viniyoga<strong> </strong>3) Viniyoga takes a highly individualized approach to supporting state change 4) The relationship between the client and the Viniyoga therapist itself promotes state change, and is very important to the state change process 5) State change is foundational to the healing process of Viniyoga. The study concluded that Viniyoga therapy can be helpful in creating state change and alleviating distress related to a wide range of physical and psychological conditions. Implications for yoga therapy as an integrative and complementary health approach are discussed.