To solve the difficulty in automatically obtaining an effective total thrust vector relative to the shield posture adjustment requirements during self-driving in soft soil strata, a shield thrust vector self-adaptive control technology for shield machines was proposed. Subsequently, a large-scale model platform was established to simulate the straight-line advancement of the testing shield machine under dynamic loads, and the feasibility of steady shield driving was verified. The test results showed that: the actual total thrust force exhibited the same variation characteristics according to load force, while a relatively fixed difference of 1000 kN between the two caused by the system friction was observed. A quick recovery after an abrupt jump of the shield speed was discovered once there was a sudden, significant change in the load. The actual resultant moment of total thrust force effectively responded to the load force, and the shield postures were maintained well. Further, the driving speed and the horizontal stroke difference were controlled in the ranges of ±3 mm/min and ±5 mm of each set values, respectively. Subsequently, this technology was applied to the Wusongkou Yangtze River Tunnel project in Shanghai, and the on-site test results verified its feasibility in actual soft soil strata. The shield speed remained stable as the actual thrust forces shared the same changing low of the target values, and a fixed difference between the two was maintained to ensure the movement of the shield machine. The variation curves of the actual steering angles in both the horizontal and vertical directions coincided with those of the target steering angles because the resultant horizontal and vertical moments of the thrust force effectively responded to each steering requirement, which was executed with high quality.