XML File Format Research Articles

Carving of the OOXML document from volatile memory using unsupervised learning techniques

With the drastic rise in digital crimes, emphasis is laid on the digital forensics to solve crimes. Evidences that are being extracted from the digital devices are now considered enough to prove a criminal guilty in the court room. While gathering the proofs from a system, a significant venue to look at is the primary memory (commonly named as RAM). A RAM holds the information about the current state of the system. It often occurs that the metadata of a file is deleted or is not available to the digital investigator. In such cases, the retrieval of the file from RAM becomes very challenging as data is placed at random locations in RAM and their allocation tables are not valid if power supply to the system is removed. While carving these instances that are randomly scattered across the RAM, their usefulness in law process cannot be ensured. Microsoft Open Office XML file Format (OOXML FF) is one of the most widely used format, yet it is not much explored in forensics (and carving). Our research intends to improve the technique of carving of an OOXML file where we have employed clustering to collect the chunks of same data based on some similarity feature. Numerous OOXML files are used in our experiments, where we have extracted and rearranged their textual contents using clustering techniques i.e. K mean and Hierarchical clustering. The results are quite encouraging and show that our proposed method can be used for carving of OOXML format. Our technique of extraction of OOXML document from the RAM reduces the hassle and saves ample time of the digital investigator who would otherwise have to go through every document available on the system to find the concerned document.

The Public Domain Song Anthology

Reviewed by: The Public Domain Song Anthology ed. by David Berger, Chuck Israels Mikkel Vad The Public Domain Song Anthology: With Modern and Traditional Harmonization. Edited by David Berger and Chuck Israels. Charlotteville, VA: Aperio Press, 2020. [Forewords in English. Available as an online resource and in print (paperback). ISBN 978173354301. $0 (electronic), print version available via donation beginning at $150.] This collection contains songs from before 1924, which are all in the public domain. In other words, these songs are not anthologized according to a genre, style, or tradition, as is common from most other songbooks, but rather according to the political economy of copyright law and its slightly arbitrary historical marker of 1924. Building on this the editors add a US national framework to the collection, as well as—perhaps most significantly and uniquely—an extra set of "modern harmonizations" in addition to the "traditional" chord changes. I shall begin by commenting on the scope and structure of the book, plus the selection of songs, before reviewing the actual songs and harmonizations which, of course, constitute the main part of the book. The motivation for the book is, admirably, to create a resource for students, teachers, and musicians who want to perform songs without risking having to pay the extra royalties that comes with playing material that is still under copyright. This will no doubt be useful for musicians wanting to play a gig of only public domain music, or for music teachers who want to organize concerts at the lowest possible cost. This is backed up by the fact that The Public Domain Song Anthology is free and easy to download as an open access, open educational resource in PDF, XML, and Sibelius file formats in addition to the physical book. These issues of copyright, public domain, and open access are the main topic of the short forewords by Robert Schwartz and Peter Jaszi, who are both lawyers. The battle of copyright and the fight for open access educational resources should be of growing concern to every musician, so it is nice to see this issue being raised here. The main editors of the volume are David Berger and Chuck Israels. Berger is a prolific composer, jazz arranger, and conductor, including as the former leader of the Jazz at Lincoln Center Orchestra, the most famous jazz repertory band in the United States. Israels is a bassist, who has played with everybody from Billie Holiday to Herbie Hancock and is best known for his work with the pianist Bill Evans and as the former director of the National Jazz Ensemble, another pioneering jazz repertory band. With the choice of big jazz names like Berger and Israels as editors and authors of the reharmonizations, the book also contributes to the well-known centering of jazz as the quintessential national music of the United States. The book is clearly meant to work, by all appearances, as a fakebook from which jazz musicians can play and jam, and the addition of the modern [End Page 635] jazz harmonizations suggests that the editors think that these songs could be added to the jazz repertoire. This makes sense, given the centrality of the Great American Songbook in the jazz world. Indeed, several of the songs in the anthology are already jazz standards (such as, After You've Gone and Who's Sorry Now), while there are others that I, frankly, would be surprised to see suddenly pop up on jazz recordings in the coming years despite a good, new harmonization and otherwise classic status (for instance, Yankee Doodle and Ta-ra-ra Boom-de-ay!). This variety is in many ways as much a strength as it is a weakness, and I certainly had fun playing some songs that I do not come across when leafing through my other fakebooks. As is clear from their forewords, Berger and Israels have been more concerned with national heritage than with copyright when putting together the anthology. David Berger begins his forward: "Living memory is not sufficient to preserve our musical heritage. Popular songs that are in the public domain (free of U.S. copyright obligation) needed to be collected and made freely available." There are...

Development and verification of code IMPC-Depletion for nuclide depletion calculation

Simulation of nuclide inventory evolution in the reactor during the entire irradiation history is of significance to the design of fuel component and core layout scheme and nuclear waste disposal. To perform accurate burnup calculations for fast reactor systems such as accelerator-driven sub-critical reactors, a nuclide depletion code IMPC-Depletion has been developed. Depletion of reactor material is described by thousands of coupled first-order ordinary differential equations, which is the stiff ODEs system. For IMPC-Depletion, algorithms including Chebyshev Rational Approximation Method (CRAM) and Transmutation Trajectory Analysis method (TTA) are implemented to solve Bateman equations. The parameter-extended XML file format is used as standard input. Decay, constant flux and power modes are supported. To verify IMPC-Depletion code, decay of Ra228, fixed-flux irradiation of Zircaloy-4 and 2.4% UO2, fixed-power irradiation of 3.2% UO2 are tested. Results are basically consistent with those of ORIGEN2.1. In addition to independent nuclides inventory analysis, IMPC-Depletion can also be coupled with Monte Carlo neutron transport code to solve burnup problem. Here, simple MOX pin cell and OECD/NEA fast reactor burnup benchmarks are employed to verify the Out-coupling Monte Carlo burnup code system IMPC-Burnup2.1, which couples OpenMC and IMPC-Depletion. Result parameters such as keff, reactivity changes and nuclides inventory values are reliable when compared with other participants.

Solar Lab Notebook (SLN): An Ultra-Portable Web-Based System for Heliophysics and High-Security Labs

This paper introduces the Solar Lab Notebook (SLN), an electronic lab notebook for improving the process of recording and sharing solar related digital information in an organized manner. SLN is a pure web-based application (available online: http://umbra.nascom.nasa.gov/sln) that runs client-side only, employing a clean and very friendly graphical user interface design, and thus providing a true cross-platform user experience. Furthermore, SLN leverages unique technologies offered by modern web browsers, such as the FileReader API, the Blob interface and Local Storage mechanism; it is coded entirely using HTML5, CSS3, and JavaScript, and powered by the extremely well documented XML file format. For high-security labs, it can be utilized as an ultra-portable and secure digital notebook solution, since it is functionally self-contained, and does not require any server-side process running on either the local or a remote system. Finally, the W3C XML Schema language is used to define a list of rules, namely a data standard, that an SLN file must conform to in order to be valid. In this way, developers are able to implement their own validation functions in their projects, or use one of the freely available tools to check if a data file is properly structured. Similarly, scientific groups at different labs can easily share information, being confident about the integrity of the exchanged data.

AUTOMATION OF MEDIA ACCESS CROSS CONNECT

Sanity testing is the process of testing the basic functionality of any software product. Sanity testing would take considerable amount of time by test engineer to test the product. If sanity testing itself fails, then the effort put on other testing techniques would go waste, as the build is declared un-usable if Sanity fails. Hence it is a good idea to automate sanity testing process so that, same sanity suite can be run as soon as a new build arrives. This automation tool is developed for a specific product, Media Access Cross Connect. The tool is being divided into two parts. First part, records all test cases in the background, whenever a test engineer performs sanity testing and saves it in XML file format. Second part, replays same configurations using a script and carries out verification and validation for the response data to decide success or failure of the test cases. It is record once run many times activity.

XML Files Types and Their Differences and Denominators with Plain TXT File

Easy and simplicity of transformation, sharing and storing files among programs, platforms and machines. From these formats are XML formats and plain and flat TXT file formats. Complex formats of the files will cause difficulty in treating with, for instance files transformation while the simple files could treat with them with insurance of no need for compatibility requirements and no virus effect. The method of this research are content size and comparison between XML file format and TXT flat file. The XML file formats are very simple to treat in structure in such as transforming and in converting among various applications. This study got that XMl files are structured programmed content and took some Kilobytes size, such as XML Spreadsheets formats which are taken for a text and a picture content just 3KB, whilst in XML PowerPoint Presentation took 97KB. TXT plain txt file is simpler than XML file which are both text based content because that, the same content after converting to TXT format took just 1KB. The plain text file format is fairly not organized and unstructured text-based content except the head section TXT file.

SU-E-T-406: Use of TrueBeam Developer Mode and API to Increase the Efficiency and Accuracy of Commissioning Measurements for the Varian EDGE Stereotactic Linac

Purpose: The Varian EDGE machine is a new stereotactic platform, combining Calypso and VisionRT localization systems with a stereotactic linac. The system includes TrueBeam DeveloperMode, making possible the use of XML-scripting for automation of linac-related tasks. This study details the use of DeveloperMode to automate commissioning tasks for Varian EDGE, thereby improving efficiency and measurement consistency. Methods: XML-scripting was used for various commissioning tasks,including couch model verification,beam-scanning,and isocenter verification. For couch measurements, point measurements were acquired for several field sizes (2×2,4×4,10×10cm{sup 2}) at 42 gantry angles for two couch-models. Measurements were acquired with variations in couch position(rails in/out,couch shifted in each of motion axes) compared to treatment planning system(TPS)-calculated values,which were logged automatically through advanced planning interface(API) scripting functionality. For beam scanning, XML-scripts were used to create custom MLC-apertures. For isocenter verification, XML-scripts were used to automate various Winston-Lutz-type tests. Results: For couch measurements, the time required for each set of angles was approximately 9 minutes. Without scripting, each set required approximately 12 minutes. Automated measurements required only one physicist, while manual measurements required at least two physicists to handle linac positions/beams and data recording. MLC apertures were generated outside of the TPS,and with the .xml file format, double-checking withoutmore » use of TPS/operator console was possible. Similar time efficiency gains were found for isocenter verification measurements Conclusion: The use of XML scripting in TrueBeam DeveloperMode allows for efficient and accurate data acquisition during commissioning. The efficiency improvement is most pronounced for iterative measurements, exemplified by the time savings for couch modeling measurements(approximately 10 hours). The scripting also allowed for creation of the files in advance without requiring access to TPS. The API scripting functionality enabled efficient creation/mining of TPS data. Finally, automation reduces the potential for human error in entering linac values at the machine console,and the script provides a log of measurements acquired for each session. This research was supported in part by a grant from Varian Medical Systems, Palo Alto, CA.« less

MS 엑셀 파일의 텍스트 셀 입력 순서에 관한 연구

스마트폰이나 태블릿 PC 사용이 보급화 되면서 장소에 구애받지 않고 실시간으로 문서의 생성과 편집이 일어나고 있다. 이처럼 학교나 회사에서 업무처리 방법의 한 부분을 차지하고 있는 문서 파일들을 분석하여 데이터가 입력되거나 편집된 흐름을 추적할 수 있다면 디지털 포렌식 수사에서 증거 자료로 활용될 수 있을 것이다. 대표적인 문서 프로그램으로 Microsoft 사의 Office 시리즈를 꼽을 수 있다. MS Office 프로그램은 복합 문서 파일 형식(Compound Document File Format)을 사용하는 97-2003 버전, OOXML 파일 형식(Office Open XML File Format)을 사용하는 2007-현재 버전까지 두 가지 파일 형식으로 구성된다. 지금까지 연구된 MS 파일에 대한 디지털 포렌식 분석 방법은 파일에 은닉된 정보를 탐지하거나 문서의 속성 정보를 통해 위변조 여부를 판단하는 것이었다. 본 논문에서는 디지털 포렌식 관점에서 MS 엑셀 파일에 텍스트 셀이 입력된 순서를 분석하여 문서의 입력 순서와 마지막으로 수정한 셀을 파악하는 방법을 연구하였다. Since smart phones or tablet PCs have been widely used recently, the users can create and edit documents anywhere in real time. If the input and edit flows of documents can be traced, it can be used as evidence in digital forensic investigation. The typical document application is the MS(Microsoft) Office. As the MS Office applications consist of two file formats that Compound Document File Format which had been used from version 97 to 2003 and OOXML(Office Open XML) File Format which has been used from version 2007 to now. The studies on MS Office files were for making a decision whether the file has been tampered or not through detection of concealed items or analysis of documents properties so far. This paper analyzed the input order of text cells on MS Excel files and shows how to figure out what cell is the last edited in digital forensic perspective.

BEAST 2: a software platform for Bayesian evolutionary analysis.

We present a new open source, extensible and flexible software platform for Bayesian evolutionary analysis called BEAST 2. This software platform is a re-design of the popular BEAST 1 platform to correct structural deficiencies that became evident as the BEAST 1 software evolved. Key among those deficiencies was the lack of post-deployment extensibility. BEAST 2 now has a fully developed package management system that allows third party developers to write additional functionality that can be directly installed to the BEAST 2 analysis platform via a package manager without requiring a new software release of the platform. This package architecture is showcased with a number of recently published new models encompassing birth-death-sampling tree priors, phylodynamics and model averaging for substitution models and site partitioning. A second major improvement is the ability to read/write the entire state of the MCMC chain to/from disk allowing it to be easily shared between multiple instances of the BEAST software. This facilitates checkpointing and better support for multi-processor and high-end computing extensions. Finally, the functionality in new packages can be easily added to the user interface (BEAUti 2) by a simple XML template-based mechanism because BEAST 2 has been re-designed to provide greater integration between the analysis engine and the user interface so that, for example BEAST and BEAUti use exactly the same XML file format.

Research and Implementation on Compression, Encryption, Storage and Retrieval System for Massive Data

A compression, encryption, storage and retrieval system for massive data is proposed and designed which can be used in these enterprises and institutions in which the business data, which need be protected, increases rapidly. In the system, XML file format is adapted as the intermediate switching format so that the detail of the multiple types of files can be omitted. A special index supporting compression and encryption is presented in the paper. In the process, the documents are stored in the server after compressed and encrypted; an end-user can retrieve the need documents efficiently by helping of the index structure. The security of the data is guaranteed since the data is not needed to be decompressed and decrypted in the retrieval process.

A validation of a ray-tracing tool used to generate bi-directional scattering distribution functions for complex fenestration systems

Fenestration attachments are anticipated to produce significant reductions in building energy use because they can be deployed quickly at low-cost. New software tools enable users to assess the building energy impacts of optically complex fenestration systems (CFS) such as shades, Venetian blinds, or daylighting systems. However, such tools require users to provide bi-directional scattering distribution function (BSDF) data that describe the solar-optical performance of the CFS. A free, open-source Radiance tool genBSDF enables users to generate BSDF data for arbitrary CFS. Prior to genBSDF, BSDF data for arbitrary fenestration systems could only be produced using either expensive software or with expensive equipment. genBSDF outputs CFS data in the Window 6 XML file format and so can be used with CFS-enabled software tools to model multi-layered window systems composed of glazing and shading layers.We explain the basis and use of the genBSDF tool and validate the tool by comparing results for four different cases to BSDF data produced via alternate methods. This validation demonstrates that BSDFs created with genBSDF are comparable to BSDFs generated analytically using TracePro and by measurement with a scanning goniophotometer. This tool is expected to support accelerated adoption of fenestration attachments and daylighting technologies.

MSV3d: database of human MisSense variants mapped to 3D protein structure

The elucidation of the complex relationships linking genotypic and phenotypic variations to protein structure is a major challenge in the post-genomic era. We present MSV3d (Database of human MisSense Variants mapped to 3D protein structure), a new database that contains detailed annotation of missense variants of all human proteins (20 199 proteins). The multi-level characterization includes details of the physico-chemical changes induced by amino acid modification, as well as information related to the conservation of the mutated residue and its position relative to functional features in the available or predicted 3D model. Major releases of the database are automatically generated and updated regularly in line with the dbSNP (database of Single Nucleotide Polymorphism) and SwissVar releases, by exploiting the extensive Décrypthon computational grid resources. The database (http://decrypthon.igbmc.fr/msv3d) is easily accessible through a simple web interface coupled to a powerful query engine and a standard web service. The content is completely or partially downloadable in XML or flat file formats.Database URL: http://decrypthon.igbmc.fr/msv3d

The Mechanics of Implementing RSS - Really Simple Syndication

RSS is a format to update the frequently updated content in the Internet such as blog entries, news headlines etc. An RSS document contains full or summarized texts plus metadata such as publishing dates and authorship. RSS stands for Really simple Syndication. RSS feeds benefits publishers by letting them syndicate content automatically. A standardized XML file format is used to publish once and viewed by many different programs.

An Object-Oriented 3-D View-Factor Code for Hohlraum Modeling

A new 3-D view-factor code has been developed to aid experiment design in indirect-drive inertial confinement fusion experiments. The code can model arbitrary user-defined hohlraum and beam configurations using a ray-tracing algorithm and an iterative approach to solving the radiosity equation. It is designed for ease of use, utilizing an open XML file format and GUI tools for rapid experiment design and evaluation. Results have been obtained and compared well with those obtained in experiment. Rendered images of the results of the code in modeling a Nova laser-driven hohlraum are presented.

Characteristics and Trends of Orthopedic Publications between 2000 and 2009

BackgroundThis study was undertaken to investigate the trends of orthopedic publications during the last decade, and to document the country of origin, journal, funding source, and language of contribution using PubMed.MethodsOrthopedic articles published between 2000 and 2009 were retrieved from PubMed using the following search terms: "orthopaedic[Affiliation] AND ("2000/1/1"[PDAT]: "2009/12/31"[PDAT])" and "orthopedic[Affiliation] AND ("2000/1/1"[PDAT]: "2009/12/31"[PDAT])." The articles were downloaded in XML file format, which contained the following information: article title, author names, journal names, publication dates, article types, languages, authors' affiliations and funding sources. These information was extracted, sorted, and rearranged using the database's management software. We investigated the annual number of published orthopedic articles worldwide and the annual rate of increase. Furthermore, the country of publication origin, journal, funding source, and language of contribution were also investigated.ResultsA total of 46,322 orthopedic articles were published and registered in PubMed in the last 10 years. The worldwide number of published orthopedic articles increased from 2,889 in 2000 to 6,909 in 2009, showing an annual increase of 384.6 articles, or an annualized compound rate of 10.2%. The United States ranked highest in the number of published orthopedic articles, followed by Japan, the United Kingdom, Germany, and the Republic of Korea. Among the orthopedic articles published worldwide during the last 10 years, 37.9% pertained studies performed in the United States. Fifty-seven point three percent (57.3%) of articles were published in journals established in the United States. Among the published orthopaedic articles, 4,747 articles (10.2%) disclosed financial support by research funds, of which 4,688 (98.8%) articles utilized research funds from the United States. Most articles were published in English (97.2%, 45,030 articles).ConclusionsThe number of published orthopedic articles has been increasing over the last decade. The number of orthopedic articles, journals publication, and funding sources were dominated by research conducted in the United States, while share and growth of Asian countries including Japan, the Republic of Korea, and China were notable.

Manufacturing Feature Modeling System Framework Based on XML and UG Platform

Feature modeling technology is the requirement of Advanced Manufacturing Technology (AMT). It is one of the key technologies of CAD/CAPP/CAM integrated system to build a shared part feature model. A feature modeling system can provide not only the geometry information of a part, but also the processing information of the part, which is needed by the latter CAM system, to realize information share and exchange between CAX systems. In the paper, feature concept, feature classification, model structure and modeling method based on features are introduced. Then, an interactive feature modeling method is presented. According to the requirement of CAPP, the system developed can supply the processing information to generate the corresponding manufacturing feature model that can be output in XML file format for a CAPP system.

A Review: Digital Rights Management Sustainable Development in e-Commerce

Strong encryption is an urgent need for e-commerce development, since it allows the privacy and secure transactions of the financial and other data. International regulations must support the spreading of e-commerce and the associated encryption techniques in order to establish a secure e-commerce environment that customers can trust and develop faith in international deployment of ecommerce solutions without restrictions. In the present paper, a pricing and license model for the fare use of the digital contents is proposed suitable for today’s digital environment. Protection by way of Digital Rights Management (DRM) systems is emerging as a natural solution because it remains in force wherever the content goes. In contrast, a file that sits on a server behind the server’s access control mechanism loses its protection once it is moved from the server. The meaning of the term “DRM” has been used so far in its most narrow sense and no longer reflects many of the recent developments in the technology used to manage copyrighted works in the digital age. The efforts made for a secure DRM approach for the secure content transactions over digital environment using latest technologies has been reviewed in the present paper to advocate finally for the most acceptable DRM architecture supporting audio, video, text, XML and other popular applications file formats to serve the dynamic needs of the market optimally.

A NOVEL APPROACH FOR CONFIGURING THE STIMULATOR OF A BCI FRAMEWORK USING XML

In a working BCI framework, all aspects must be considered as an integral part that contributes to the successful operation of a BCI system. This also includes the development of robust but flexible stimulator, especially the one that closely related to the feedback of a BCI system. This paper describes a novel approach in providing flexible visual stimulator using XML which has been applied for a BCI (brain-computer interface) framework. Using XML file format for configuring the visual stimulator of a BCI system, we can develop BCI applications which can accommodate many experiment strategies in BCI research. The BCI framework and its configuration platform is developed using C++ programming language which incorporate Qt’s most powerful XML parser named QXmlStream. The implementation and experiment shows that the XML configuration file can be well executed within the proposed BCI framework. Beside its capability in presenting flexible flickering frequencies and text formatting for SSVEP-based BCI, the configuration platform also provides 3 shapes, 16 colors, and 5 distinct feedback bars. It is not necessary to increase the number of shapes nor colors since those parameters are less important for the BCI stimulator. The proposed method can then be extended to enhance the usability of currently existed BCI framework such as BF++ Toys and BCI 2000.

Standards and infrastructure for managing experimental metadata

Abstract*See also "related poster":http://precedings.nature.com/documents/3144/version/1*Today’s researchers can perform biological and biomedical studies where the same material is run through a wide range of assays, comprising several technologies such as genomics, transcriptomics, proteomics and metabol/nomics (hereafter referred as ‘omics’). To enable others to correctly interpret the complex data sets that result, and the conclusions drawn, it is necessary to provide contextualizing experimental metadata at an appropriate level of granularity.Standards initiatives normally cater to particular domains. However, several synergistic standards activities foster cross-domain harmonization of the three kinds of reporting standard (minimum information checklists, ontologies and file formats). Some 29 groups participate in the "MIBBI":http://www.mibbi.org project, which offers a one-stop shop for those exploring the range of extant ‘minimum information’ checklists, and which fosters integrative development^1^. More than 60 groups participate in the "OBO Foundry":http://www.obofoundry.org ^2^, which coordinates the orthogonal development of ontologies such as "OBI":http://obi-ontology.org for describing experimental (meta)data. And several groups participate in the development of "ISA-Tab":http://isatab.sf.net, a tabular framework for presenting experimental metadata^3^ (analogous to "FuGE":http://fuge.sf.net, a generic data model to underpin various XML file formats^4^).We have developed an infrastructure that leverages the aforementioned synergistic reporting standards to create a common structured representation and storage mechanism for experimental metadata from biological and biomedical investigations ranging from simple single-assay studies to complex, methodologically diverse multi-assay studies.View the "public instance":http://www.ebi.ac.uk/bioinvindex of our ISA-based infrastructure, running at EBI, and/or "download the components":http://isatab.sf.net for your local use.*References*1. Taylor CF, Field D, Sansone SA,… Rocca-Serra P et al. (2008) The MIBBI Project. Nature Biotechnology Aug;26(8):889-896. "http://www.mibbi.org":http://www.mibbi.org2. Smith B, Ashburner M, Rosse C,… Rocca-Serra P, …Sansone SA et al. (2007) The OBO Foundry. Nature Biotechnology Nov;25(11):1251-5. "http://www.obofoundry.org":http://www.obofoundry.org3. Sansone SA, Rocca-Serra P, Brandizi M,… Taylor CF et al. (2008) The First MGED RSBI (ISA-TAB) Workshop. OMICS. Jun;12(2):143-9. "http://isatab.sf.net":http://isatab.sf.net4. Jones AR, Miller M, Aebersold R,… Sansone SA et al. (2007) The Functional Genomics Experiment model (FuGE). Nature Biotechnology Oct;25(10):1127-1133. "http://fuge.sf.net":http://fuge.sf.net

Standards and infrastructure for managing experimental metadata

Abstract*See also the "related presentation":http://precedings.nature.com/documents/3145/version/1*We present an infrastructure that leverages synergistic reporting standards and ontologies^1,2,3,4,5^ to create a common structured representation and storage mechanism for experimental metadata from biological and biomedical investigations ranging from simple single-assay studies to complex, methodologically diverse multi-assay studies.The infrastructure’s components include: a data capture and editing tool (ISAcreator); validator (ISAvalidator); database (BioInvestigation Index); and converter (ISAconverter); and a BioConductor analysis package (R-ISApackage). The components are designed for local installation, and can work independently, or as unified system.View the "public instance":http://www.ebi.ac.uk/bioinvindex running at EBI and/or "download the components":http://isatab.sf.net for your local use.*References*1. Taylor CF, Field D, Sansone SA,… Rocca-Serra P et al. (2008) The MIBBI Project. Nature Biotechnology Aug;26(8):889-896. "http://www.mibbi.org":http://www.mibbi.org2. Smith B, Ashburner M, Rosse C,… Rocca-Serra P, …Sansone SA et al. (2007) The OBO Foundry. Nature Biotechnology Nov;25(11):1251-5. "http://www.obofoundry.org":http://www.obofoundry.org3. Ontology for Biomedical Investigations (OBI) "http://obi-ontology.org":http://obi-ontology.org4. Sansone SA, Rocca-Serra P, Brandizi M,… Taylor CF et al. (2008) The First MGED RSBI (ISA-TAB) Workshop. OMICS. Jun;12(2):143-9. "http://isatab.sf.net":http://isatab.sf.net5. Jones AR, Miller M, Aebersold R,… Sansone SA et al. (2007) The Functional Genomics Experiment model (FuGE). Nature Biotechnology Oct;25(10):1127-1133. "http://fuge.sf.net":http://fuge.sf.net