The Junggar Basin in the northern Xinjiang Province, northwestern China, is a large hydrocarbon basin with tremendous reserves of oil, gas and coals. Tens of sandstone-type uranium showings, occurrences and/or anomalies have also been discovered in the Junggar Basin since the 1960s, yet hitherto only one large uranium deposit, the Kamusite deposit, has been identified in the Middle Jurassic Toutunhe Formation sandstones in the eastern part of the basin. Sand bodies with high-permeability are the prerequisite for the formation of the in situ leachable sandstone-hosted uranium deposit, nevertheless the spatial distribution and genetic types of the sand bodies, as well as the deposition model in Jurassic time in the Kamusite area both remain unclear, which largely hindered the understanding of the sedimentary evolution and uranium exploration directions in the region.In this contribution, based on the outcrop observation, core logging and well logging data interpretation, and comprehensive analysis, the sedimentary characteristics, sedimentary facies types, sand body morphology, plane distribution characteristics, as well as the sedimentary evolution history in Jurassic time in the Kamusite area have been illustrated in details. From early to late, the Jurassic sediments in Kamusite can be divided into the Badaowan, Sangonghe, Xishanyao, Toutunhe and Qigu formations, of which the sand bodies favorable for the sandstone-type uranium mineralization have been systematically analyzed, and the depositional model in the Kamusite area have been established. The Early Jurassic Badaowan Formation is a set of coal-bearing coarse-grained clastic sediments of the braided river–braided river delta facies, followed by the lake transgression and fine-grained lacustrine deposition in the Sangonghe Formation. The Middle Jurassic Xishanyao Formation is a set of braided river delta facies coal-bearing clastic sediments, while the uranium orebody-bearing Toutunhe Formation underwent the paleoclimate transition from warm and humid to hot and arid, and developed a set of braided river delta to meandering river facies sequences with an overall positive sedimentary rhythm. The Qigu Formation is dominated by a series of meandering river to lacustrine facies fine-grained sediments and largely denuded by later tectonic activities. Three sets of sand bodies favorable for the sandstone-type uranium mineralization are recognized, including those in the lower Toutunhe Formation, the lower Xishanyao Formation, and the upper Badaowan Formation, from bottom to top. A four-stage sedimentary evolution model from the Badaowan Formation to the Toutunhe Formation has been established thereafter, and general exploration suggestions were proposed in the last of the contribution. More drilling is recommended to the south of the Kalasayi Fault, aiming the lower Toutunhe, lower Xishanyao and upper Badaowan formations. To the north of the Kalasayi Fault, more uranium mineralization could also be expected, and the exploration is suggested to focus on the Jurassic Toutunhe, Xishanyao formations and Cretaceous Tugulu Group.