ObjectiveVenous stents are a common treatment modality for obstructive venous disease. Venous stents differentiate themselves by either a woven or braided structure, open or closed cell arrangement or based on material composition (elgiloy vs. nitinol). Changes in the morphology of venous stents over time may contribute to restenosis or thrombosis. Woven elgiloy stents are prone to proximal and distal edge deformation compared to dedicated venous stents which offer increased radial force at stent edges. The objective of this study is to describe luminal morphological changes among various venous stents and between woven to non-woven venous stent configuration, over time. MethodsA retrospective review at a single institution between January 2014-June 2021 identified patients treated with venous stents. Patients with iliac and/or femoral venous stents with intraoperative intravascular ultrasound (IVUS) and a post-operative computed tomography (CT) scan were included in the study. Cross-sectional diameters measurements were taken at proximal, middle, and distal portions of each stent from intravascular ultrasound (IVUS) at the time of initial stenting and compared to the cross-sectional diameter measurements taken from CT imaging at follow-up. A paired t-test was used to compare the luminal change with a D’Agostino-Pearson test used for normality. ResultsFifty-four stents distributed amongst thirty-eight patients were identified. Mean time to follow-up was 17.5 months. Stents were placed in the common iliac vein (n=37, 68.5%), external iliac vein (n=14, 25.9%), and common femoral vein (n=3, 5.6%). Implanted stents included the Boston Scientific Wallstent (n=23, 42.6%), Bard Venovo (n=3, 5.6%), Boston Scientific Vici (n=23, 42.6%), and Medtronic Abre (n=5, 9.3%). The mean luminal loss was measured at 2.12 mm proximally (95% confidence interval (CI), 1.64-2.60; p<0.001), 1.29 mm at the mid-stent (95% CI, 0.83-1.74, p<0.001) and 1.56 mm distally (95% CI, 0.99-2.12; p<0.001). There was no significant difference in luminal changes between woven and non-woven stents at proximal (p=0.374), middle (p=0.179), and distal (p=0.609) stent measurements. ConclusionThis study reports morphological changes within venous stents and between woven and non-woven venous stents. Our findings demonstrate that the edge-stent luminal reduction traditionally attributed to woven configurations also occurs with the newer non-woven stents. Additional factors such as anatomic location, pelvic curvature or other external forces may be accountable for this change rather than geometrical configuration of the stent.