Building a science & technology’s world leader is an important goal for China by 2035, how to build a strong country in science and technology - high-level scientific talent is the fundamental supporting factor. Historically, Germany, the United States and Japan, three late-developing catching-up countries in the process of moving towards a scientific and technological power, have successfully implemented high-level scientific talent training initiatives, ultimately promoting the strong rise of science and technology. According to the experience of the three countries, the cultivation of high-level scientific talents is mainly achieved through major reforms in education, especially research-oriented education reform. At present, China is entering a new stage of development in building a scientific and technological power, the domestic and international development situation is more severe, and the law of science and technology itself is evolving at an accelerated pace, which puts forward new requirements for the cultivation of high-level scientific talents, and education reform is imperative. In comparison with the experience of Germany, the United States and Japan, China's current high-level research-oriented education still has many problems, it is difficult to support self-reliance and self-improvement in science & technology and build China into a world leader in science & technology. To sum up the history and face the reality, it is suggested that China should establish the concept of "integration of science and education" as soon as possible, promote education reform under the traction of scientific and technological needs, comprehensively sort out and reshape the positioning of universities, accelerate the reform of high-level research education, and increase the reform of primary and secondary education to prepare for the cultivation of high-level scientific talents in a comprehensive and systematic way.