World Experience Research Articles

PROBLEMS AND PROSPECTS OF THE DEVELOPMENT OF BANKING REGULATION AND SUPERVISION IN UKRAINE

Effective banking regulation and supervision are key factors for ensuring the stability of the national banking system of Ukraine. The purpose of this article is to analyze the peculiarities of banking regulation and supervision in Ukraine in order to identify problems and possible ways of development, including in the context of world experience. The article examines the theoretical aspects of the essence of the concepts of banking regulation and banking supervision. The main indicators of the banking system of Ukraine for 2020-2024 and the mechanism for identifying risks in the activities of banking institutions are also considered. The global trends in banking regulation at the current stage are its centralization, the concept of risk-oriented supervision, the introduction of new financial technologies, the development of the principles of proportional banking regulation. The main positive and negative methods of supervision in the banking sector are singled out. It has been proven that the conditions of a full-scale military conflict significantly undermined the development of the banking system of Ukraine. The destruction of infrastructure, loss of customer confidence, risks to the bank's loan portfolio and capitalization have become major problems. In addition, the decrease in liquidity and the growth of inflation risks create serious challenges for the banking system. The degree of suitability of world models in terms of the priority tasks of the state regarding the regulation of the banking sector is analyzed. Directions for improving banking supervision through improvement of banking activity licensing procedures are proposed; introduction of permanent monitoring of the activities of domestic commercial banks, in particular their financial condition; implementation of constant monitoring of compliance with banking regulations and current legislation; introduction of permanent inspections of banking activities; implementation by commercial banks of ongoing internal control and external audit control; developing and sending supervisory instructions for banking institutions regarding the implementation of Basel III standards.

Event tourism in Azerbaijan: current state and mechanisms for its improvement in the context of world experience

Event tourism is a dynamically developing sector of the global tourism industry, the share of which increases by 1.5% annually. This segment plays a key role in stimulating the local economy, attracting investment and developing cultural exchange. In Azerbaijan, which has a rich historical and cultural heritage, event tourism has significant potential. However, its development in the regions faces a number of problems that need to be addressed for more efficient use of existing opportunities. This article discusses the current state of event tourism in Azerbaijan, studies certain events held in the republic, substantiates its importance for the socio-economic development of the country’s regions and proposes mechanisms for its improvement based on international experience. The purpose of this article is to analyse the current state of event tourism in Azerbaijan, assess its potential for the socio-economic development of regions and develop recommendations for its improvement, considering existing problems and prospects. The object of the study is to identify problems and explore opportunities related to the development of event tourism in Azerbaijan. The subject of the research is the mechanisms for improving event tourism in the regions of Azerbaijan, including the analysis of current problems, assessment of potential and development of recommendations for improving the accompanying infrastructure, financing, marketing and other key aspects in the context of studying and applying foreign experience. The work uses an analytical research method based on a review of scientific papers in the field of event tourism.

Patient and public involvement in the design of an international clinical trial: real world experience

BackgroundThe value of patient and public involvement (PPI) during the earliest stages of clinical trial development, and prior to the award of substantive funding, is widely recognised. However, it is often under-resourced and PPI processes during this phase are rarely reported in detail. Having benefitted from seed funding to develop an international clinical trial proposal, we sought to describe and appraise PPI activities and processes that support pre-award co-development.MethodsA 12-month “accelerator” award facilitated development of a substantive funding application to deliver the Rheumatoid Arthritis Prevention PlatfORm Trial (RAPPORT), conceived to prioritise preventative interventions for people at risk of RA. PPI partners, including individuals at risk of rheumatoid arthritis (RA), RA patients, relatives and members of the public, provided feedback on key trial design issues through online meetings, a feedback form and emails. PPI processes employed during the one-year accelerator project were thereafter evaluated by PPI partners using an anonymous online feedback form with reference to National Institute of Health and Care Research (NIHR) UK standards for public involvement in research.ResultsSixteen out of the 25-strong PPI partner panel completed an online feedback form (64%). Respondents perceived PPI processes positively in relation to all NIHR standard domains. Several key facilitators and challenges were identified, including the need for adequate PPI funding during pre-award phases of research, strategies for creating an inclusive environment, flexibility around levels of involvement, and challenges in achieving representatively diverse participation, and the importance of communicating transparent processes for role-assignment and time-reimbursement.ConclusionsIn general, RAPPORT was considered an example of PPI well done, and in line with UK standards for public involvement in research. Facilitators and challenges of relevance for the development of future translational and clinical trial funding applications are highlighted.

Qualifying Assets as Strategic Intellectual Potential for Innovation Development of the EAEU

It has been noted that in the legislative acts of the United States and the European Union, clauses have appeared indicating an intensification of the process of assessing qualifying assets, which has never happened in history. Naturally, this extraordinary step raises the need to identify the reasons motivating this phenomenon. A logical assumption has been made about the existence of a connection between this event and an attempt to create countermeasures on the part of the US leadership to the threat of the fall of the dollar as an international currency.Aim. Such a large-scale assessment exercise is considered from the point of view of its enormous potential economic effect and is proposed for use, but in the direction of a completely different goal — the development of proposals not only and not so much for the assessment of qualifying assets, but for the use of this assessment as a stimulus for economic growth and growth in the well-being of workers within the EAEU member countries.Tasks. Investigation of the proposed qualifying asset valuation exercise. Conducting an analysis of problems associated with the widespread practice of taking into account valuations in the authorized capital of enterprises of the EAEU member countries.Methods. A systematic approach to studying the problem of valuation and accounting of qualifying assets. Study and analysis of many years of world experience in the problems of practical assessment of human capital and capitalization of intellectual property in Russia and abroad.Results. The way to use the assessment of qualifying assets and accounting in the authorized capital of enterprises is shown in the interests of accelerating their joint innovative development of the EAEU member countries, as well as stimulating and increasing the importance of education and living standards in general.Conclusions. The process of assessing and accounting for qualifying assets in the authorized capital of an enterprise, in principle, as a progressive phenomenon, is inevitable, it is only a matter of time. For the EAEU member countries, the introduction of this process into practice will accelerate their innovative development and increase the social significance of higher education. Similar conclusions should be extended to the BRICS and SCO member countries.

A Brief Analysis of Symbolic Metaphors in Korean Drama Squid Game

In the US TV series dominate the Netflix platform today, Squid Game as the first Korean series to top the 2021 Netflix platform US series list, has won a high reputation around the world experience is worth in-depth analysis, there are many domestic and foreign scholars on Squid Game this popular Korean drama analysis. The purpose of this study is to briefly explore what symbolic metaphors are used in the Squid Game and the role they play in the series, as well as to analyze what role symbolic metaphors play in the communication of the series. Using the research method of questionnaire survey, this research concluded that the Squid Game uses symbolic metaphor to simplify complex metaphors, mechanisms, characters, and social realities, and uses symbols to show them. Such setting “smoothing” the cultural differences of the series “decoded” by audiences from different countries, and promoted the plot development in narrative. The multiple functions of revealing characters’ hearts and reflecting the theme of the series have promoted the global spread of the TV series Squid Game.

Real world experience in treatment of chronic hepatitis C in patients with compensated and decompensated cirrhosis

Real world experience in treatment of chronic hepatitis C in patients with compensated and decompensated cirrhosis

Some legal aspects of personal data protection in the world—experience for Vietnam

Some legal aspects of personal data protection in the world—experience for Vietnam

Gender differences in the treatment with PCSK9 monoclonal antibodies real world experience from a dedicated prevention clinic

Abstract Background Proprotein convertase subtilisin/kexin type 9 monoclonal antibodies (PCSK9 mAb) lower low-density lipoprotein cholesterol (LDL-C) levels and reduce atherosclerotic cardiovascular disease (ASCVD). There are gender differences in PCSK9 biological characteristics, which are not properly addressed in current data. Purpose Examining gender differences in treatment with PCSK9 mAb. Methods A retrospective study based on data from the Prevention Cardiology Clinic in Rabin Medical Center. Included were patients prescribed with PCSK9 mAb (evolocumab or alirocumab), for primary or secondary prevention. Data included medical background and treatment variables. Response to treatment was evaluated by changes in LDL-C at 3 and 12 months. Data was analyzed by gender. Results Study included 246 patients (mean age 67y, ASCVD 78.8%, mean baseline LDL-C 128.2 mg/dL). Women (42% of cohort) prescribed with PCSK9 mAb were older than men (69 vs. 65 years, respectively; p<0.001). The dominant indication for PCSK9 mAb for both genders was secondary prevention, while primary prevention indication was more prevalent in women vs. men (39.4% vs. 16.3%, respectively; p<0.001). Statin intolerance was observed in 82.4% and 58.6% were treated with combination therapy with PCSK9 mAb, without significant gender differences. Baseline mean LDL-C was higher among women vs. men (138.9 vs. 117.3 mg/dL; p<0.001). Overall, high adherence was observed (91.8% and 79.7% at 3 and 12 months, respectively). After 1-year, adherent men had lower LDL-C levels than women (46.8 mg/d and 61.9 mg/dL, respectively; P=0.001), and were more likely to reach their LDL-C therapy goals; below 70 mg/dL (76.1% vs. 62.2%, respectively; P=0.032) and below 55 mg/dL (60.1% vs. 39.8% respectively; P=0.003). Conclusions In patients treated with PCSK9 mAb, gender differences exist in prescription age, indications, baseline LDL-C and achieved LDL-C goals. In this study adherence to PCSK9 mAb was higher than reported before, possibly due to surveillance in a dedicated prevention clinic.LDL-C & Non-HDL-C levels under PCSK9 mABSex Differences in acheived LDL-C goals

Educational management in personnel training of hydrometeorological services: world experience

Introduction. The relevance of the presented study is determined by the fact that the acceleration of climate change on the planet has a significant impact on almost all spheres of economic and social life of mankind, which imposes new requirements both on the information provided by hydrometeorological services and on the personnel of managers and specialists providing it.Purpose setting. The purpose of the presented studies is to summarize the world experience in the development of promising requirements for the skills and competence of managers and specialists of national meteorological services in the interests of forming a system of requirements for staffing and training of managers and specialists of hydrometeorological services of the Roshydromet system.Methodology and methods of the study. The methodological base of the research consists of well-known scientific works devoted to the promising requirements for the skills and competencies of managers and specialists of the hydrometeorological service. Results. The novelty of the obtained results lies in the fact that, based on the generalization of world experience in the development of promising requirements for the skills and competence of managers and specialists of national hydrometeorological services, it was found that when forming personnel management strategies, on the one hand, requirements are put forward for a wide range of competencies of personnel who own both traditional technologies and innovative technologies for processing and interpreting information based on IT. On the other hand, hydrometeorological services impose increased demands on themselves, which is manifested in strategic aspirations to form a holistic motivation system for their employees, covering all levels of human needs, according to substantive theories of motivation – from economic competitiveness to opportunities for training, development and self-expression.Conclusion. The practical significance of the obtained results lies in the possibility of using world experience in developing promising requirements for the skills and competence of managers and specialists of national meteorological services when forming strategies for personnel management of hydrometeorological structures of the Roshydromet system.

War veterans’ retraining: development of educational programmes for economic recovery in Ukraine

ABSTRACT This article aims to analyse the world experience of retraining war veterans in order to restore the economy and consider possible ways of implementing the acquired knowledge and practices in the context of Ukraine. A study was conducted to identify the basic needs and challenges faced by veterans and examine the key aspects of the challenges that war veterans experience when entering the civilian labour market. The authors analyse effective approaches and programmes already applied in various countries, including the United States, in order to overcome these difficulties and promote veterans’ integration into society and the economy. These include at the local level, or with the patronage of non-governmental organisations, educational programmes for retraining veterans in Ukraine. The authors offer specific recommendations for the development and implementation of specialised educational programmes for retraining veterans in Ukraine at the state level, mainly based on advanced world practice and existing local experience. Finally, particular attention is paid to the aspects of adaptation and implementation of these programmes in Ukrainian realities at the national level.

P2.14A.02 Assessment of Immunohistochemical Panel Utilization in Thymic Carcinoma Diagnosis: Real World Experience Insights

P2.14A.02 Assessment of Immunohistochemical Panel Utilization in Thymic Carcinoma Diagnosis: Real World Experience Insights

Role of mineral elements in the nutrition of garden strawberry plants

Relevance. The increase in global production of garden strawberry fruit is due to the high demand for the products for fresh consumption and as raw material for processing. The leading countries are: PRC, USA, Turkey, Egypt, Mexico, Spain, Russia, Poland, South Korea, Brazil. Increase in production volumes is provided due to high productivity of new varieties and intensification of strawberry cultivation technologies and, in particular, plant nutrition. The possibility of managing the nutrition of garden strawberry plants is one of the priority tasks from the solution of which depends on the realization of the potential of plant productivity, as well as the quality of the resulting products The role of many macroand microelements in plant nutrition is not fully understood. Numerous studies are conducted to identify the mechanisms of their absorption and movement in strawberry plants. New forms of fertilizers are being studied, allowing to effectively influence the processes of growth and development of plants, minimize the impact on the environment.Results. The article is devoted to the review of the role of the main mineral macroand microelements in plant nutrition, such as nitrogen, phosphorus, potassium, magnesium, calcium, iron, silicon, molybdenum. Based on the analysis of literary sources, the influence of certain mineral elements on physiological processes associated with the growth and development of garden strawberries is considered. The data on reaction of plants to the optimal content, excess and deficiency of certain elements, possibilities of their receipt and assimilation by plants of garden strawberries are given. Application in practice of the world experience on management of mineral nutrition can significantly improve the existing technologies of strawberry cultivation in open and protected ground.

Dive Into the Past: Chinese Intangible Cultural Heritage Represented in Chinese Mobile Games

This study delves into the representation of intangible Chinese cultural heritage in Chinese mobile games. Nowadays, even with huge economic potential, Chinese mobile games are still faced with negative comments, especially from parents. To develop their reputation, Chinese mobile games have portrayed considerate Chinese intangible cultural heritage (ICH). The representation of cultural heritage in video games has been a subject of discussion for a long time, while console and computer games and tangible cultural heritage have been at the centre of academic studies. Hence, we strived to investigate how Chinese ICH is depicted in Chinese mobile games. A thematic analysis was conducted on data collected through analytical gameplay of 30 Chinese mobile games selected from Apple’s App Store and the Chinese TapTap platform. Our analysis indicates that Chinese ICH is represented in Chinese mobile games to fulfil the persona of game characters, to create a more engaging and immersive game world experience, to provide more intense combat moments, to offer visually enjoyable virtual goods, and to deliver culturally driven updates during traditional festivals. Among the various forms of Chinese ICH, Chinese traditional craftsmanship is found to be used most frequently because of the huge effort it requires to be mastered, which could be educational to players. Theatrical traditions were found to be depicted in most game elements because they combine visual, audio, and motional elements. Lastly, folk and classical literature is portrayed in Chinese mobile games to provide a narrative resource that culturally resonates with players.

DEVELOPMENT OF MARKETING IN AZERBAIJAN

The main goal of the article is to study activities aimed at marketing development in Azerbaijan. It is noted that benefiting from the synthesis of the national characteristics of the economy (including the experience of the Soviet era) and the world experience is one of the urgent requirements of the modern era. Method and methodologies. In the analysis process, comparative analysis of statistical indicators, analysis of legal-normative documents necessary for the development of marketing, classification of existing problems in the system of formation of market relations in Azerbaijan, forecasting and projecting methods were used. Novelty on the article. The article focuses on some rational and non-rational activities that are neglected in the scientific literature and necessitates the development of marketing. Conclusion and suggestions. The article emphasizes that marketing promotion is a step that serves to make companies popular among the population. These steps are one of the necessary steps to be carried out and updated both thoroughly and systematically. It is noted that 90% of managers of companies operating in Azerbaijan think that there is no need for marketing research. Thus, the decision to implement marketing measures is not based on the analysis of research data, and this, in turn, does not justify the effectiveness of marketing projects. Businessmen rely too much on their intuition and make unreasonable expenses based only on their own experience and unsystematized information that reaches them over a period of time. As a result: 1. Unsuccessful image campaigns are organized that do not produce any desired intangible effect; 2. Sales of newly launched products are falling; 3. Preference is given to advertising campaigns mainly aimed at financial impact; 4. Absurd models of brand perception emerge as a result of lack of study of brand perception after marketing activities; 5. Low level of service and, as a result, customer satisfaction. At best, marketers refer to a company's to-do list.

Telemedicine technologies in allergology: implementation experience in clinical practice, problems and perspectives

In 2020, the need for widespread restriction of social contacts around the world has raised the issue of alternative types of medical care and, in particular, the development of online consultations with physicians of subspecialties. However, even before the Covid-19 pandemic, telemedicine technologies were demonstrating their ability to save financial and time resources, increase access to health services and improve adherence to treatment for patients with allergic diseases. Despite some technical and legal difficulties associated with the organization of remote appointments, the clinic of the National Research Center – Institute of Immunology Federal Medical-Biological Agency managed to successfully implement a platform for telemedicine consultations. During the period from 1.09.2020 to 19.04.2024, 4675 patients were consulted, 945 of whom filled out a questionnaire on the quality of medical care provided. According to the results of analyzing the obtained data, we observed high patient satisfaction with the new medical service as well as economic profitability of the project. The purpose of this article is to provide a visual overview of the world and domestic experience of telemedicine implementation in the clinical practice of an allergist, to tell about the way of organization and operation of the platform for telemedicine consultations in the National Research Center – Institute of Immunology Federal Medical-Biological Agency, and to highlight the current state of the problem.

Incomplete Immunity for Varicella and Measles in Pediatric Organ Transplant Candidates. Real World Experience From an Infectious Diseases Pre-Transplantation Clinic.

Vaccinating pediatric solid organ transplant candidates against measles and varicella is crucial due to the risk of severe disease in immunosuppressed recipients and general avoidance of live virus vaccines post-transplantation. The world saw a resurgence of measles starting 2012 prompting the American Society of Transplantation in 2015 to release guidelines on recognition, prevention, and post-exposure prophylaxis of this disease in solid transplant recipients. This study aims to assess the extent of incomplete immunity to these viruses in candidates and the approach to immunity optimization during a period of heightened awareness. A cross-sectional study from 2012 to 2016 at Cleveland Clinic Children's included pediatric solid organ transplant candidates. Data on vaccination history, serology, and demographics were collected. Incomplete immunity was defined by incomplete vaccination or seronegativity. Among 91 candidates, 54.9% had complete varicella vaccination. Serological varicella immunity among patients tested varied by age: < 7 years, 50.0% positive in patients with complete schedules, none in the incomplete; ≥ 7 years, 50.0% positive in patients with complete schedules, 65.5% in the incomplete. For measles, 69.2% had complete vaccination, with immunity varying by age among those tested: < 7 years, 84.6% positive in patients with complete schedules, 42.9% in the incomplete; ≥ 7 years, 81.0% with complete, 62.5% with incomplete. Only 31.1% of those who qualified for a varicella additional dose and 28% who qualified for an additional measles dose received it, respectively. Incomplete immunity to varicella and measles was prevalent in pediatric solid organ transplant candidates at our center during the study period. Despite an increase in global measles activity, our efforts to optimize immunity through additional vaccine doses were only partially successful. Future research should focus on addressing strategies and understanding barriers to ensure timely vaccination for this vulnerable population prior to transplant, especially during periods of increased viral activity.

Real world experience with cladribine tablets in the management of relapsing multiple sclerosis in Qatar

ObjectivesTo study the 30-month safety and effectiveness of Cladribine tablets (CladT) in relapsing multiple sclerosis (RMS) months in a real-world setting. MethodsRetrospective single-centre observational study in Qatar (January 2018–Feb 2023). Clinical and MRI data, lymphocyte counts and adverse events (AE) were recorded for patients with RMS who received at least one course of CladT. ResultsForty-six patients were included (mean follow-up 22 months); 34 (74%) were female, 22 (48%) were disease-modifying therapy (DMT) naïve, 16 (35%) had switched from platform DMT and 8 (17%) from high efficacy (HE) DMD. Mean age was 26.7±7.2y, mean disease duration was 7.2±6.0y. Common reasons for treatment with CladT were MS activity (91%), pregnancy planning (17%), AE (20%), compliance (9%). 44/46 ( 96%) received the year 2 course of CladT. Annualised relapse rate (ARR) fell from 1.02 (baseline) to 0.1, 0, 0.1, 0.1 and 0.1 for years 1–5 post-treatment, respectively; 87.5–100% were free of relapses at these times, vs. 21% at baseline. There were no relapses in year 2; 78%, 100%, 84%, 80% and 100%, respectively, were free of GD+ MRI lesions at years 1–5, vs. 31% at baseline. Most clinical AE were mild (1 moderate, no severe AE); 12 contracted Covid-19 (no hospitalisations). Grade 3 lymphopenia occurred in 5 patients. ConclusionsCladT appeared to be effective and safe in our retrospective study, irrespective of prior treatments, consistent with other real world data that support the early use of CladT in the management of RRMS.

368 Real World Experience Using a Rapid Test to Distinguish Bacterial From Viral Infection in the Emergency Department

368 Real World Experience Using a Rapid Test to Distinguish Bacterial From Viral Infection in the Emergency Department

Incorporation of Cystatin C Testing in Clinical Practice: Real World Experience in Sweden

Incorporation of Cystatin C Testing in Clinical Practice: Real World Experience in Sweden

TCT-76 Percutaneous Coronary Intervention in High-Risk Patients With High Syntax Score Left Main Coronary Disease: 17-Year Long-Term Follow-Up Real World Experience of a Single Center Without On-Site Cardiac Surgery

TCT-76 Percutaneous Coronary Intervention in High-Risk Patients With High Syntax Score Left Main Coronary Disease: 17-Year Long-Term Follow-Up Real World Experience of a Single Center Without On-Site Cardiac Surgery