The study entitled, “Effect of Using Information Communication Technologies in Teacher Education on Prospective Teachers Learning”. Major research objective was to analyze the effect of ICTs on prospective teachers learning. Sample of the study consisted of 300 prospective Teachers and 20 teacher educators of south Punjab universities. Five public sector universities including the IUB Bahawalpur, GSCWU Bahawalpur, UE Multan, NUML Multan Campus, and BZU Multan. The researcher collected data from students of M.Ed. last semester. The study was survey and descriptive in nature. The quantitative as well as qualitative (QUAN-qual) approach was adopted. The questionnaire was used for data collection from prospective teachers and interview from teacher educators. The descriptive and inferential statistics were applied. The study concluded that prospective teachers understand better when teacher integration ICTs in their class lecture and they understand better when identify and retrieve information from a range of sources of ICTs, fell pleasure and accelerate learning through ICTs. They acquire communication skills for workplace preparedness. There was insignificance difference between opinion of male and female teacher. Likewise, majority of teacher educators agreed that prospective teachers gain technological knowledge, through ICTs. They may improve keen interest and research habits as ICTs promote motivation, practice, affective learning.