Creep-feed grinding is a high-efficiency, high-precision grinding process widely used in the manufacturing of aviation engines. However, the workpiece burn and other quality issues caused by high processing temperature limit the yield of grinding. Therefore, the accurate model of grinding temperature has become the key to improving processing efficiency and quality. Different from the traditional physical or data-driven models, this paper attempts to combine both perspectives based on Physics-Guided Neural Networks (PGNN) to accurately predict grinding temperature with a small number of experiments. At the level of data acquisition, real grinding experiment data was obtained and a data augmentation method had been proposed. At the level of neural network structure, optimisation processes were implemented to enhance prediction performance, and a physics-guided loss function was inserted to guide network training. The experiment results shows that PGNN had better prediction accuracy than the physical model, while also mitigating the limitations of data-driven models on small sample sets. PGNN also performed better with noisy data and predictions out of the training data range, this reveals the benefits of PGNN for small sample problems in processing scenarios.