Adentia, whether partial or complete, is a common condition in the population, especially among older individuals. Although removable orthodontic devices are an effective solution for adentia, dentures can cause irritation in the oral cavity. The nature and duration of symptoms experienced by patients using dentures for the first time depend on various factors, such as the condition of their teeth and gums, jaw bone density, prosthesis design, psychological factors, and previous dental work. Studies have shown that special adhesive agents can improve the fit of removable dentures, leading to faster adaptation and better stability, even in challenging oral conditions. Using adhesives not only helps with new prostheses but also enhances comfort with existing ones, reduces movement while eating, and prevents food from getting trapped under the denture. This ultimately improves the patient's psychological well-being, reduces the foreign body sensation, and enhances quality of life. Proper maintenance and use of removable dentures can prevent jaw bone atrophy and degenerative changes in the oral tissues. Literature review revealed the numerous variables that impact the successful treatment of total or partial tooth loss in patients. The incorporation of bonding agents unquestionably enhances the adjustment process to removable orthodontic devices by enhancing stability, a critical factor in the early stages of prosthesis use. However, it is essential to consider other various factors that influence the complexity and duration of adaptation, such as the characteristics of the dental structure, oral mucosa condition, jaw bone atrophy level, prosthesis selection and design, patient's psychological state, presence of macroglossia, previous prosthetic work, or its absence.
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