Objective. The research of clinical features, reproductive health and sexual disorders with women of childbearing age, involved in HIV epidemic.Materials and methods. Cross-sectional, cohort, clinical sociological research of gynecological pathology and comorbid conditions among 85 women with HIV infection. The results of sociological research by anonymous survey among 50 women and 35 men of reproductive age with HIV infection are presented. The research was held using a questionnaire, based on WHO thematic map-questionnaire (WHO project №88093).Results and discussion. The main group with HIV infection and reproductive disorders contains 27 women (median age 30,8±2,9). The comparison group consisted of 23 women with HIV infection without reproductive disorders (median age 31,4±7,1). The frequency of medical abortion appeared twice as often in the group of HIV-infected women with reproductive disorders. Statistically significant differences in occurrence of chronically related diseases: ENT organs, gastritis/duodenitis, pancreatitis, cystitis, pyelonerphritis, viral hepatitis (В, С), Papilloma Viral Infection in the compared groups has not been identified. The women with HIV infection and reproductive disorders experienced inflammatory disease of pelvic organs, provoked by chlamydia, gonorrhea, trichomoniasis, syphilis twice as often. Statistically significant differences in occurrence of hysteromyoma, chronic cervicitis, chronic endometritis, vulvovaginal candidiasis, cervical intraepithelial neoplasia haven’t been detected. Menstrual function analysis among the women with HIV infection and reproductive disorders identified a considerable predominance of secondary amenorrhea, opsomenorrhea, secondary oligomenorrhea and dysmenorrhea. The women with HIV infection and reproductive disorders experienced hyperprolactinemia syndrome 3 times as often. The men were married more often than the women, had regular sexual intercourse, were not interested in their partners’ pregnancy. The most common method of contraception for women as well as for men was contraception sheath and rejected sexual intercourse. However, 20% and 26% men and women with HIV infection, who had sexual intercourse, didn’t use any methods of contraception. The main reason for both men and women to refuse pregnancy planning was unsatisfactory financial situation and having current HIV infection.Conclusion. Early diagnosis of menstrual disorders, prevention of abortion and sexually transmitted diseases, and also early infertility treatment are necessary for women with HIV infection. Apart from medical care, medical workers should take into account social and psychological needs to help patients with HIV improve their quality of living, including sexual and reproductive health.