Coiba Island and the associated Special Zone of Marine Protection represent an important, yet poorly studied marine reserve along the Pacific coast of Panama. While efforts have recently began to establish monitoring programs in the region, a range of historical, marine-related environmental measurements already exist, derived from satellite-based observations. The goal of this paper was to use long-term datasets for key variables to provide qualitative insights (i.e. descriptive oceanography) of climatological conditions and interannual variability in the Pacific Panama region. These are underpinned with numerical assessments, providing an important baseline for ongoing and future studies, particularly in the Coiba Island/Gulf of Chiriqui region. In particular, we examined 20 years (January 2003-December 2022) of wind stress, sea surface temperature (SST), and chlorophyll-a (Chl-a), spanning the neritic and pelagic regions of the Pacific Panama coast. During the dry season (northern winter), the well-known, seasonal, regional Panama wind jet appeared across the Gulf of Panama, leading to surface mixing and SST cooling that eventually extended across most of the Panama Bight. West of the Azuero Peninsula, SST increased and surface warming extended further offshore from January through April. The SST in the Gulf of Chiriqui during this period was about 1 °C warmer on average than east of Coiba Island. By July and August, offshore SST gradients became largely longitudinal, cooling occured across the season, and the SST on either side of Coiba Island was nearly the same. The influence of the Panama jet in the Gulf of Panama was clear in the Chl-a data as well, with upwelling-driven values peaking in February/March (up to 11 mg m-3, with a monthly climatological value of around 2 mg m-3 during this period). During the rest of the year, the Chl-a concentration in this region averaged around 0.5-1.0 mg m-3. In the Gulf of Chiriqui and the region east of Coiba Island, the climatological monthly averages were roughly 0.3-0.5 mg m-3 and 0.4-0.6 mg m-3, respectively. Somewhat surprisingly, very high Chl-a values were present in the satellite data for the Gulf of Chiriqui during May 2007 and June 2008, peaking at 16 mg m-3 and 32 mg m-3 at a location just west of Coiba Island, respectively. It remains unclear as to the cause of these apparent blooms. Even when the high Chl-a values were excluded in the calculation of climatological averages in the Gulf of Chiriqui, however, there is a suggestion of modest seasonality in Chl-a values, with slightly elevated values (~ 0.4 mg m-3) peaking around May and October. During the extreme El Niño event of 2015-2016, the monthly-averaged SST along the Panama Pacific coast was warmer than average, with elevated levels of up to + 2 °C and lasting 12 months in the Gulf of Chiriqui. In the Gulf of Panama, the monthly-averaged SST anomalies were up to + 1.7 °C, although the temperatures returned to near-seasonal averages after roughly 5 months.