Abstract This scientific article delves into the intricacies of wind flow's impact on multi-storey buildings, presenting results from a series of experimental investigations. The research encompasses an examination of wind interactions with buildings of varying heights and geometric profiles. Furthermore, it unveils the effects of tall structures on the natural ventilation and smoke evacuation systems of shorter edifices, considering different wind flow directions. The study leverages specialized wind tunnel and measurement techniques for a comprehensive analysis of wind-induced loads on buildings. The acquired insights furnish crucial input for the design of single-story temporary modular constructions within densely populated urban areas, subject to wind-induced stresses. Additionally, they hold potential applicability in the advancement of energy-efficient technologies and strategies within the realm of construction. The acquired dataset underscores the criticality of scrutinizing wind flow's impact on structures of varied typologies and dimensions and will allow to significantly improve the quality and efficiency of modern buildings in the future.