Widening Of Periodontal Ligament Space Research Articles

Scleroderma: oral, maxillofacial and radiographic manifestations for dental practitioners.

Scleroderma is an autoimmune condition of unknown aetiology with a range of manifestations, which can be limited to the skin or can extend to be multisystemic. It is characterised by fibrosis, microangiopathy and dysregulation of the immune system and commonly affects the oral cavity. Frequent oral and maxillofacial features include fibrosis of the face, circumoral furrows and reduced oral aperture. Radiographic findings are often incidental, including uniform, asymptomatic periodontal ligament space widening of teeth and osteolysis of bone at muscular attachments. The oral and maxillofacial manifestations significantly contribute to its disease burden and are often overlooked and undertreated as their treatment can be limited due to their challenging rheumatological care. Given the complexity of the condition and its multisystemic impacts, better co-operation between dentists and rheumatologists may help improve this patient cohort's quality of life. This clinical article aims to better equip dentists to identify features of scleroderma and manage the day-to-day oro-facial manifestations.

Assessment of Mesiobuccal Canals in Endodontically Treated Teeth in Indore Population by Cone Beam Computed Tomography: A Cross-Sectional Study.

Owing to the complicated anatomical nature of maxillary molars, untreated root canals may directly affect the outcome of root canal therapy. Therefore, cone beam computed tomography (CBCT) scanis an important tool in the evaluation of root canal systems, particularly for the detection of the second mesiobuccal(MB2) canalin maxillary molars. The current study was undertaken to detect and evaluate filled/unfilled MB2 canals in endodontically treated, asymptomatic maxillary molars, and its correlation with periapical pathology by utilizing cone beam computed tomography (CBCT). A retrospective study of 80 CBCTs of patients underwent scanning for various treatment modalities, with asymptomatic endodontically treated permanent maxillary first molars selected. Data collection occurred between January and June 2023. CBCT machine used was KODAK 9000 (Rochester, NY: Carestream Health) (Complementary Metal Oxide Semiconductor {CMOS} sensor, continuous mode and 12-28 sec scan time, 90-500 μm voxel size, and 5x3.5 cm field of view {FOV}). The axial images at mid-root level were used to assess the presence of the MB2 canal. The study included 39 (48.8%) right maxillary first molars and 41 (51.3%) left maxillary first molars. Overall, in 62 (77.5%) maxillary first molars, MB2 was missed by the practicing dentist, and in 13 (16.3%) maxillary first molars MB2 canal was not present. Of all the maxillary first molars with MB2 canal (n=67), 53 (79.1%) canals had a periapical infection, five (7.5%) showed widening of periodontal ligament space whereas nine (13.4%) had no abnormality. MB2 canals were present in the majority of cases and most of the unfilled MB2 canals showed evidence of periapical radiolucencies and showed a direct impact on the prognosis.

Influence of systemic sclerosis on periodontal health: A case-control study.

Patients with systemic sclerosis (SSc) present various clinical and radiological oral manifestations. However, precise evaluation of the oral features associated with diffuse cutaneous SSc (dcSSc) and limited cutaneous SSc (lcSSc) is limited. The objective of this study was to evaluate the periodontal ligament (PDL) surface in SSc patients in comparison with controls. Assessment of oral-health-related quality of life (OHRQoL) and the levels of different biomarkers in the gingival crevicular fluid (GCF) was performed. SSc patients and matched controls underwent standardized oral examination and cone-beam computed tomography (CBCT). Levels of interleukin-6 (IL-6), chemokine (C-X-C motif) ligand 4 (CXCL-4) and matrix metalloproteinase-9 (MMP-9) in the GCF were determined by enzyme-linked immunosorbent assay. PDL surface was measured on CBCT axial views. OHRQoL was quantified using the Mouth Handicap in SSc Scale (MHISS). Thirty-nine SSc patients and 39 controls were included. SSc patients exhibited increased PDL surface, higher number of missing teeth as well as elevated IL-6, MMP-9 and CXCL-4 levels. Reduced mouth opening was observed in dcSSc but not in lcSSc patients. MHISS score was higher in dcSSc than in lcSSc patients. Although worse periodontal parameters were found in both subgroups compared with controls, dcSSc patients presented lower gingival inflammation. SSc is associated with PDL space widening, impaired oral health and OHRQoL.

Radiographic signs of occlusal trauma are associated with marginal bone loss: a retrospective clinical study.

Work in animal models has implicated excessive occlusal forces and occlusal trauma as co-destructive factors for periodontitis. The main aim of the present study was to make a radiographic assessment of the effects of excessive occlusal forces i.e. occlusal/incisal tooth wear (TW), widening of the periodontal space (PDLw), and the presence of a mandibular torus (TM), on interproximal marginal bone loss (MBL) in a large series of patients. A secondary aim was to evaluate the statistical correlation between the parameters in specific two teeth and those of 12 teeth for MBL and six teeth for TW within the same individual. A total of 1950 full-mouth radiographic surveys were analyzed retrospectively. MBL was quantified relative to the root length ("Schei's ruler technique"). In addition, TW and PDL widening of the periodontal space were assessed, as well as the presence of TM. Odds ratio and logistic regression analysis were used to determine the association between occlusal trauma and MBL. The correlation of the measured parameters between the values for specific teeth and the whole dentition was evaluated from data from the first 400 radiographs. Teeth 41 and 33 showed the best correlation to the whole dentition: 0.85 for MBL, 0.83 for PDLw, and 0.97 for TW. The results of a logistic regression analysis with age as an independent variable, revealed a significant association between bone loss and both tooth wear (OR=2.767) and bone loss and PDLw (OR=2.585). TW is positively correlated to both PDLw and MBL. No correlation was found between the presence of TM and MBL.

Missed canal as a factor affecting the periapical status

Aim. To identify the relationship between the presence of a "missed" root canal and the periapical status.Materials and methods. 500 CBCT images of patients of both sexes were studied: 2915 teeth after endodontic treatment, of which 1549 were multicanal. Profile diagnostic criteria were used to identify the "missed" canal.Results. 518 "missed" root canals were revealed, which accounted for 33.4% of the number of multi-canal teeth. In 228 cases, changes in periapical tissues were noted, including 1 case of widening of periodontal ligament space, which accounted for 44% of the total number of "missed" canals. It was noted that the risk of developing apical periodontitis is higher for cases with "missed" canals (p < 0.001). The relationship between the untreated canal and the periapical status is statistically assessed as medium or relatively strong, which confirms the relevance of accurate diagnosis of the anatomy and topography of the root canal system at all stages and by all available methods.Conclusions. In case of sufficient duration of observation, absence of symptoms, absence of periapical changes (radiologically) – repeated treatment for the purpose of endodontic treatment of the "missed" root canal is not justified. If there are changes in the periapical tissues, repeated endodontic intervention should be performed. In this case, preference should be given to endodontic re-treatment using a microscope.

Bilateral resorption of mandibular angle in patient with systematic sclerosis - a case report

Progressive systemic sclerosis (PSS) is chronic autoimmune disease affecting a connective tissue. The symptoms of PSS in orofacial area are: restricted mouth opening, xerostomia, facial asymmetry and problems with oral hygiene. Radiographic images can show specific features like bone resorption, especially in mandibular region or periodontal ligament space widening. The aim of this study was to present the case of 56-year-old woman with characteristic scleroderma-related changes visible on panoramic radiograph. The patient diagnosed with severe systemic sclerosis was referred by dermatologist to general dentist. The woman experienced tightening of facial skin, xerostomia and reduced mouth opening which caused problems with daily oral hygiene and dental treatment. General dentist referred the patient to the Department of Dental and Maxillofacial Radiodiagnostics of Medical University of Lublin for the panoramic X-ray. One of the main findings was bilateral resorption of mandibular angles. Localization of the bone resorption in patients with scleroderma is related to attachements of masticatory muscles. Dentists and general doctors should be aware that some of the maxillofacial manifestations of systematic scleroderma can be visible on panoramic radiographs.

Comparative Evaluation of the Efficacy of Light-Cured Calcium Hydroxide and a Fourth-Generation Calcium Silicate Cement (TheraCal LC) as Indirect Pulp Capping Materials in Patients With Deep Carious Lesions: A Randomized Parallel-Group Clinical Trial.

AimThe current study aims to evaluate and compare the efficacy of light-cured calcium hydroxide and a fourth-generation calcium silicate cement (TheraCal LC®) as indirect pulp capping (IPC) materials in patients with deep carious lesions.Materials and methodsA total of 28 patients were randomly divided into two groups (n=14). Group A was managed by light-cured calcium hydroxide, while group B was treated with TheraCal LC (a fourth-generation calcium silicate cement). Clinical examination was conducted to check for postoperative pain, tenderness, and neural sensibility, and radiographical examination was conducted to check for periodontal ligament space widening, presence of calcific barrier, and periapical radiolucency at patient recall of 21 days, three months, and six months. Primary and secondary outcome variables were based on clinical and radiographical success rates noted at six months’ follow-up.ResultsSuccess rate for light-cured calcium hydroxide group at follow-up came out to be 0% at 21 days, 85.71% at three months, and 92.85% at six months. The success rate for TheraCal LC group came out to be 0% at 21 days, 92.85% at three months, and 100% at six months. The overall success rate for IPC procedure was 89.28% at three months’ follow-up and 96.42% at six months’ follow-up for both groups. The difference was statistically non-significant at the end of three and six months’ follow-up.ConclusionWithin the limitations of our study, it was concluded that TheraCal LC can be used alternatively with light-cured calcium hydroxide in IPC, with a predictability of similar success outcome in patients with deep carious lesions.

Follow Up on Simple (Closed) Extraction of Fractured Maxillary Canine Teeth in Domestic Ferrets (Mustela putorius furo).

Fractured canine teeth (especially maxillary canine teeth) are common in domestic ferrets (Mustela putorius furo). We evaluated (detailed oral/dental and radiographic examination under general anesthesia) 18 domestic ferrets affected by 23 complicated crown fractures of periodontally healthy permanent maxillary canine teeth over a 2-year period. Average age of the ferrets at the time of diagnosis was 2.6 years. Only three teeth were discolored on clinical examination. Out of 23 teeth, 22 were radiographically evaluated. No radiographic evidence of endodontic disease was observed in 11/22 canine teeth. Inflammatory root resorption was observed in 5/22, periapical lucency in 5/22 teeth, apical widening of periodontal ligament space in 6/22 teeth, and failure of the pulp cavity to narrow in 3/22 teeth. All animals were treated by simple (closed) extraction of the affected teeth. Histological examination of eight teeth was performed. Pulp appeared histologically vital in five (3/5 showed no radiographic evidence of endodontic disease), pulpitis was diagnosed in two (both without radiographic evidence of endodontic disease) and pulp necrosis in one case (dental radiographs revealed apical widening of periodontal ligament space and failure of the pulp cavity to narrow). All extraction sites healed uneventfully by the 2-week recheck examination. Long-term follow-up revealed development of post-extraction upper lip entrapment with mandibular canine tooth in eight out of 18 ferrets, which appeared clinically irrelevant. According to clients seven out of 18 ferrets showed an improved quality of life. Simple tooth extractions are warranted in ferrets affected by complicated crown fracture of the periodontally healthy permanent maxillary canine teeth.

The Radiological Assessment of Root Features and Periodontal Structures in Endodontically Treated Teeth Subjected to Forces Generated by Fixed Orthodontic Appliances. A Prospective, Clinical Cohort Study.

The various side effects of orthodontic treatment with fixed orthodontic appliances (FOAs) and their impact on apical and periodontal structures have been widely reported. However, the existing data is not yet conclusive. Aims and objectives: To investigate the status of roots and periodontium in endodontically treated teeth that have undergone orthodontic treatment with the use of FOAs and to evaluate their impact on apical/periodontal structures. Material and methods: The prospective clinical cohort study initially involved 69 participants aged 16–40, without underlying systemic conditions, who received orthodontic treatment with ligatureless FOA systems due to different types of mild and moderate malocclusions. To meet the required criteria, 88 teeth in 34 patients were assessed clinically and radiologically. Participants had at least one tooth treated endodontically while the corresponding tooth from the same anatomical group on the opposite side was vital and intact (a ‘split-mouth’ approach). Four cohorts were allocated: Group IA consisted of 15 teeth, treated utilising the principles of modern endodontics, that were subjected to orthodontic forces no less than six months after completing the root canal obturation. Group I consisted of 13 similarly endodontically treated teeth, which commenced orthodontic treatment at least six months after the completed endodontic therapy. Group II contained 16 teeth treated by conventional endodontic methods and the control group, Group III, contained 44 clinically and radiologically intact teeth (incisors and premolars) with vital and sound dental pulp. The response of apical and periodontal structures to FOAs was determined by data collected from intraoral periapical radiographs taken within the course of five consecutive appointments during the orthodontic treatment. Results: No statistically significant differences were observed in susceptibility to FOA-induced external apical root resorption (EARR) between combined Groups IA + IB and II. An association was, however, demonstrated, between the occurrence of EARR and the degree of expansion of the periodontal ligament (PDL) space, regardless the method of root canal treatment. Cumulative data revealed a positive correlation between the width of the PDL space and the stage of FOA treatment (the third and the fourth appointment). The subtle changes in radiological length of roots have been observed (min 0 mm/max 0.38 mm), particularly between the second and third appointment in Group II (p < 0.05). Conclusions: The standard orthodontic therapy with FOAs is a safe option with predictable outcome for persons who have recently received endodontic therapy. The anterior teeth, predominantly incisors, were more susceptible to minimal EARR than premolars, which suggests that the rate of EARR occurrence may depend upon the original morphology of the apical portion of the root. The use of additional orthodontic forces increases the risk of EARR and is associated with a higher incidence of radiologically detected PDL space widening.

Analysis of Panoramic Images of Orthodontic Patients

Panoramic imaging is the most widely requested radiographic technique in dentistry. In orthodontics, the clinical and radiographic examinations are routinely carried out along with dental and skeletal photographs as a part of diagnosis and treatment planning. The evaluation of radiographs of patients after orthodontic treatment is important in understanding the possible changes that tend to occur post-treatment. This study aims to analyze the incidental findings present in the radiographs of patients who previously underwent orthodontic treatment. A total of 30 patients (18 females; 12 male) were randomly selected from the Orthodontic clinic at the Department of Orthodontics, Saveetha Dental College and Hospital, Chennai. Two independent examiners analyzed the panoramic radiographs for anomalies and pathologies. The result showed the most common finding, which was periodontal pathology (Generalised bone loss, widening of periodontal ligament space, or both, loss of lamina dura) with a prevalence of 36.7%. All the patients taken into the study had at least one anomaly. In conclusion, the relevant findings were observed in all the radiographs &amp; special care should be taken while evaluating them to diagnose alterations that may require other dental treatments.

Computed tomographic findings of dental disease in domestic rabbits (Oryctolagus cuniculus): 100 cases (2009-2017).

To characterize the CT findings and epidemiological features of acquired dental disease in rabbits. 100 client-owned rabbits (Oryctolagus cuniculus). Medical records were searched to identify rabbits that underwent skull CT for any reason from 2009 to 2017. History, signalment, and physical examination findings were recorded. The CT images were reevaluated retrospectively for evidence of dental disease and graded according to a previously described system (from 1 [no evidence of disease] to 5 [severe dental disease]) for acquired dental disease in rabbits, and an overall (mean) grade was assigned. Descriptive analyses were performed. Factors were assessed for associations between dental disease grade and malocclusion stage. Common findings included premolar or molar tooth curvature in transverse (n = 100 rabbits) and sagittal (95) planes, apical elongation of premolar or molar teeth (99), sharp dental points (93), deformation of the mandibular canal (82), and periodontal ligament space widening (76). Acquired dental disease was classified as grade 1 (n = 2 rabbits), 2 (60), 3 (14), 4 (4), or 5 (20). Most CT findings were significantly correlated with each other. Agreement of grades was fair between left- and right-sided quadrants and between maxillary and mandibular quadrants. Age was associated with increasing dental disease grade and malocclusion stage (proportional ORs, 1.21 and 1.32/y, respectively). Fair agreement in disease grades between dental quadrant pairs indicated a degree of asynchrony in the development of dental disease. Findings suggested premolar or molar tooth curvature in a sagittal plane, subtle elongation at premolar or molar tooth apices, and mandibular canal deformation should be added to the grading system.

Tail of the whale appearance: A pathognomonic feature of scleroderma

Scleroderma is a rare connective tissue disorder of unknown etiology characterized by fibrosis of skin, blood vessels, and internal organs. Orofacial changes include mask-like facies, microstomia, xerostomia, and stiffness of tongue with reduced mouth opening. The radiographic features are very characteristic which includes symmetrical widening of periodontal ligament space and bone resorption. We, hereby present a case of 55-year-old female patient of Scleroderma presenting with a typical radiographic feature of “Tail of the whale” appearance due to resorption of the ramus of mandible.

Two calcium silicate-based materials used in direct pulp capping (in-vivo study)

Aim The aim was to clinically and radiographically evaluate mineral trioxide aggregate (MTA) and TheraCal LC as direct pulp capping (DPC) materials. Materials and methods Twenty male patients aged 17–35 years with immediate mechanical pulp exposure in lower molars were randomly divided into two equal groups (n = 10). Group 1: pulp exposures were capped using MTA. Group 2: pulp exposures were capped using TheraCal LC. Immediately after DPC, a base-line digital bitewing and periapical radiographs were taken. Clinical evaluation was performed at 1, 4, 12, and 24 weeks after DPC for presence/absence of spontaneous pain, tenderness to percussion, draining sinuses and pulp response to thermal pulp vitality test. At 24 weeks after DPC, digital periapical, and bitewing radiographs were taken. Digitalized bitewing radiographs were submitted to image analysis software to measure dentin bridge thickness in comparison to the base-line bitewing radiographic image. Digitalized preoperative and postoperative periapical radiographs were submitted to the same software to evaluate changes in the width of periodontal ligament space. Results Clinically, all cases showed criteria of successful treatment except 3, four cases in groups 1 and 2, respectively. Statistical analysis revealed no statistically significant difference between both groups (P > 0.05). All of the thirteen cases that were available for evaluation after 6 months showed dentin bridge formation. In MTA group, the mean value of dentin bridge formed was higher than in TheraCal LC group with no statistically significant difference (P = 0.710). Changes in the width of periodontal ligament space were not significantly different between both groups recording (P > 0.05). Conclusion Clinically and radiographically, MTA and TheraCal LC are favorable materials for DPC inducing adequate dentin bridge formation and minimal widening of periodontal ligament space.

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Tomographic study of Jaw bone changes in patients with bisphosphonate-related osteonecrosis.

BackgroundBisphosphonates (BP) are synthetic pyrophosphate-like substances with antiresorptive properties and specifically affect osteoclastic activity. In 2007, the American Association of Oral and Maxillofacial Surgeons (AAOMS) defined diagnostic criteria for Osteonecrosis of the Jaws Associated with Bisphosponates (BRONJ). BRONJ is mainly diagnosed by clinical features, but the detection of early bone changes by imaging may help prevent and better understand the disease. The objective of this study was to evaluate maxillary changes in CBCT in patients using BP. Material and MethodsAll included patients were diagnosed with osteonecrosis and received bisphosphonate drugs in the last ten years. All imaging examinations were obtained by I-CAT and 3D Accuitomo. The multiplanar reconstructions were analyzed by an examiner without knowledge of the clinical aspects and location of the lesions. ResultsThe study sample consisted of 21 patients, the majority of the sample represented patients with cancer (76.2%), the other patients had osteoporosis (23.8%). Only four patients (19.04%) received alendronate, while intravenous bisphosphonates, such as zoledronate and pamidronate, represented the treatment of most of our sample. Most of our patients presented stage 1 and 2 MRONJ (85.7%), whose lesions were mainly observed in the mandible (52.4%). Fifty-seven percent of the patients had at least one bone change. Conclusions In BRONJ, bone changes vary between exposed and non-exposed areas and one aspect of the study was: persistent extraction cavities in the BRONJ lesion region and high frequency of periodontal ligament space widening in areas that are not involved in BRONJ lesions. This reflects the very important role of dental and periodontal diseases in the pathophysiology of BRONJ. Thus, preventive measures should be prioritized for patients exposed to anti-resorptive drugs. Key words:Cone-Beam computed tomography, osteonecrosis, bisphosphonate-associated osteonecrosis of the jaw.

Effect of Vitamin C on Tooth Movement in Terms of Periodontal Ligament Space in Guinea Pigs

Periodontal ligaments are one of the supporting tissues of teeth that undergo remodeling during the tooth movement process. Vitamin C deficiency inhibits the regeneration of collagen fibers, which are important in tissue remodeling that affects the widening of the periodontal ligament space during the process of tooth movement. The widening of periodontal ligament space can be seen by taking radiographic photos. The purpose of this study was to determine the width of the periodontal ligament space of guinea pigs by administering vitamin C, without vitamin C, and the differences between the two groups. Those samples were grouped into four groups with observation times of 1, 4, 7, and 10 days, and each group consisted of the control group and vitamin C group. Those samples were paired with orthodontic separator rubber. After the specified time was completed, periapical radiographs were taken, and the width of the periodontal ligament space was measured by using Image J software. The mean width of the periodontal ligament space in the vitamin C group was smaller than the control group. Based on this study, it can be concluded that vitamin C has an effect on reducing periodontal ligament space in the process of tooth movement.&#x0D; &#x0D; Key words: periodontal ligament space, vitamin C, tooth movement, remodeling

Endodontic Retreatment Using Reciprocal File System in Underfilled Root Canal: A Case Report

Underfills in endodontic treatment increases failure rates by 14%. A 23-year-old female patient came with chief complaint of slight pain on #35. The periapical radiograph showed underfilled root canal and periodontal ligament space widening. The root canal filling was removed with reciprocal file system. Follow-up visit showed no recurrence pain and the tooth function was fully restored using a fiber-reinforced post and an all-ceramic crown.

Volumetric Cone Beam Computed Tomography for the Assessment of Oral Manifestations in Systemic Sclerosis: Data from an EUSTAR Cohort.

Background: Oral health issues are commonly reported in systemic sclerosis (SSc), comprising a broad spectrum of manifestations, e.g., reduced mouth opening, periodontal disease, increased periodontal ligament (PDL) space width, and mandibular resorption. We aimed to assess oral radiographic abnormalities, particularly PDL space widening and erosions, and to identify potential relations with disease measures. Methods: cross-sectional study in 43 SSc and matching controls receiving systematic oral assessments (full mouth dental/periodontal) and imaging (radiographs and cone beam computed tomography (CBCT)). Associations between disease variables and radiologic findings were investigated by univariate and multivariate analysis (SPSS-v.20, p < 0.05). Results: CBCT demonstrated generalized PDL space widening in up to half SSc, with at least one tooth involved, essentially in the posterior region (p < 0.05). Significant correlations between number of teeth with PDL space widening and disease severity, skin score, disease subset, topoisomerase I specificity, age, and disease duration were reported (p < 0.05). Additionally, mandibular erosions were described in one out of four patients, commonly condylar erosions. Conclusions: Tridimensional CBCT approach confirmed widening of PDL and mandibular erosions as common dental findings in scleroderma. Furthermore, widened PDL spaces correlated with several disease characteristics including severity, skin extent, and antibody profile.

Clinical performance of mineral trioxide aggregate versus calcium hydroxide as indirect pulp-capping agents in permanent teeth: A systematic review and meta-analysis

Aims and Objectives: The aim of this study was to compare the clinical performance of mineral trioxide aggregate (MTA) and calcium hydroxide as indirect pulp-capping agents in permanent teeth. Materials and Methods: Search strategy includes randomized control trials and clinical trials from the databases of PubMed Central, Cochrane, EBSCO, and MEDLINE from January 1998 to May 2018. A total of six clinical trials that met all inclusion criteria were included in this systematic review. Meta-analysis was performed for three among the included studies. The primary clinical outcome of the included studies was to evaluate the pulp vitality with a normal response to thermal, electrical, and tactile tests without signs of spontaneous pain. The radiological outcome was to evaluate the absence of periapical radiolucency, periodontal ligament space widening, and the dentin bridge formation. The primary and predominant results were assessed based on the success or failure of pulp capping. The restorations were considered failure when there are clinical symptoms such as pain and tenderness and radiographic evidence of radiolucency in periapical region or widening of periodontal ligament. Results: In the six trials that are included, two studies are judged as low risk and four as medium risk of bias. With the help of meta-analysis, the evidence produced concluded that after six-month and one-year follow-up there was no statistically significant difference between MTA and calcium hydroxide as an indirect pulp-capping material. Conclusion: This systematic review of the available evidence reveals that MTA and calcium hydroxide demonstrated good consistent endurance in clinical studies and indistinguishable performance.

Dental considerations in diagnosis of maxillary sinus carcinoma: A patient series of 24 cases

BackgroundMaxillary sinus carcinoma is a rare entity with an incidence of 0.2% and a low patient survival rate due to the frequency of late diagnosis. MethodsIn this multicenter, transversal, retrospective, observational study, the authors analyzed patients who had received a diagnosis of maxillary sinus carcinoma, registering their oral symptoms, histologic type, treatment efficacy, and survival rate. ResultsMaxillary sinus carcinoma was diagnosed in 24 patients (15 men and 9 women), of which 75% were squamous cell carcinomas. All patients had dental mobility, and some had swelling, orosinus fistula, or some dental loss. Mean patient survival rate was 38.83 months. ConclusionsA history of pain or swelling of unknown origin, an unexplained widening of periodontal ligament space, or mobility of the teeth should be considered warning signs of maxillary sinus carcinoma. Practical ImplicationsRecognition of oral symptoms by the dentist would help in making an early diagnosis of maxillary sinus carcinoma, improving the patient’s chances of survival and quality of life.